Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: The Efficacy of Allo-HSCT in ND HR-CBF-AML
A clinical trial sponsored by Ruijin Hospital is evaluating the efficacy of allogeneic hematopoietic stem cell transplantation in newly diag…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Olutasidenib Combined With Co-targeted Therapy in Relapsed or Refractory IDH1-mutated Myeloid Malignancies Harboring Activated Signaling Pathway Mutations [Phase 2]
This entry outlines a Phase 2 clinical trial testing olutasidenib in combination with a co-targeted therapy for relapsed or refractory IDH1-…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Venetoclax and Sequential Busulfan, Cladribine, and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndrome [Phase 2]
Phase 2 trial update evaluating venetoclax with sequential busulfan, cladribine, and fludarabine phosphate as conditioning before donor stem…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Single-arm, Prospective Study of a Clad-LABU Conditioning Regimen in HSCT for R/R MDS/AML in Elderly Patients [NA]
A single-arm, prospective study evaluating a Clad-LABU conditioning regimen in hematopoietic stem cell transplantation for elderly patients …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Testing the Addition of an Anti-cancer Drug, SNDX-5613, to the Standard Chemotherapy Treatment (Daunorubicin and Cytarabine) for Newly Diagnosed Patients With Acute Myeloid Leukemia That Has Changes in NPM1 or MLL/KMT2A Gene [Phase 1]
A Phase 1 clinical trial assessing adding SNDX-5613 to standard daunorubicin/cytarabine chemotherapy for newly diagnosed acute myeloid leuke…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Multi-modality Imaging and Collection of Biospecimen Samples in Understanding Bone Marrow Changes in Patients With Acute Myeloid Leukemia Undergoing TBI and Chemotherapy [EARLY_Phase 1]
An early-phase study at City of Hope evaluating imaging techniques and biospecimen collection to understand bone marrow changes in patients …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Palbociclib and Sorafenib, Decitabine, or Dexamethasone in Treating Patients With Recurrent or Refractory Leukemia [Phase 1]
A Phase 1 clinical trial from MD Anderson tests combinations of palbociclib with sorafenib, decitabine, or dexamethasone in patients with re…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Trial of Orca-T Following Reduced Intensity or Nonmyeloablative Conditioning in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 2]
This entry describes a Phase 2 clinical trial evaluating Orca-T after reduced-intensity or nonmyeloablative conditioning in patients with ac…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A High Intensity Electronic Health Intervention for the Reduction of Learning Disparities in Childhood Cancer Survivors [NA]
A clinical trial update describing a high-intensity electronic health intervention aimed at reducing learning disparities among childhood ca…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating CD45RA-depleted stem cell addback to prevent viral or fungal infections following TCRab/CD19-deplet…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Massage Impact on Sleep in Pediatric Oncology [NA]
A pediatric oncology clinical trial from Children's Hospital of Philadelphia is investigating whether massage can improve sleep for children…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: MiRisten for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
Phase 1 clinical trial update for MiRisten to treat relapsed or refractory acute myeloid leukemia. The study is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Creation of a Biocollection of Patients With Acute Myeloid Leukemia (AML) or Lymphoid Leukemia (ALL) or High-risk Myelodysplastic Syndrome (MDS) Monitored at the Nantes University Hospital
This clinical trial update describes the creation of a biocollection of patients with acute myeloid leukemia, acute lymphoblastic leukemia, …
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Phase I-II Study Investigating the All-Oral Combination of the Menin Inhibitor SNDX-5613 With Decitabine/Cedazuridine (ASTX727) and Venetoclax in Acute Myeloid Leukemia (SAVE) [Phase 1, Phase 2]
A Phase I–II trial in Acute Myeloid Leukemia evaluating an all-oral combination of the menin inhibitor SNDX-5613 (revumenib) with decitabine…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia [Phase 1]
This Clinical Trial Update describes an ongoing Phase 1 study evaluating the safety and tolerability of ziftomenib in combination regimens f…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Tagraxofusp and Low-Intensity Chemotherapy for CD123-Positive Relapsed or Refractory AML [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating Tagraxofusp in combination with a low-intensity chemotherapy regimen for CD123-positive relapsed or re…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: ONC201 in Treating Patients With Relapsed or Refractory Acute Leukemia or High-Risk Myelodysplastic Syndrome [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating ONC201 for relapsed or refractory acute lymphoblastic leukemia, relapsed or refractory acute mye…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) [Phase 3]
Phase 3 clinical trial evaluating a three-drug combination of Bleximenib, Venetoclax, and Azacitidine for newly diagnosed acute myeloid leuk…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Vaccine (VSV-hIFNβ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or Lymphoma [Phase 1]
A Phase 1 clinical trial evaluating the VSV-hIFNβ-NIS vaccine with or without cyclophosphamide and in combination with ipilimumab, nivolumab…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Venetoclax in Combination With Cladribine and Cytarabine Alternating With Azacitidine Plus Venetoclax for the Treatment of Newly Diagnosed Monocytic AML and Active Signaling Mutated AML [Phase 2]
Phase 2 clinical trial evaluating venetoclax in combination with cladribine and cytarabine alternating with azacitidine plus venetoclax for …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Addition of an Anti-cancer Drug, M3814, to the Usual Treatment (Mitoxantrone, Etoposide, and Cytarabine) for Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
Phase 1 trial assessing addition of M3814 (peposertib) to the standard mitoxantrone, etoposide, and cytarabine regimen for relapsed or refra…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Bortezomib, Sorafenib Tosylate, and Decitabine in Treating Patients With Acute Myeloid Leukemia [Phase 1]
Phase 1 clinical trial evaluating a three-drug combination (bortezomib, sorafenib tosylate, and decitabine) in adults with acute myeloid leu…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of 14C-Bleximenib (Radiolabeled) in Participants With Acute Leukemia [Phase 1]
A Phase 1 clinical trial evaluating a radiolabeled 14C-Bleximenib in patients with acute leukemia. The study is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapies [Phase 1]
This document reports on the status update for a Phase 1 trial of Bleximenib in combination with AML-directed therapies for acute myeloid le…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Comparing Different Treatment Lengths for Venetoclax in Older People With Newly Diagnosed Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial) [Phase 2]
A Phase 2 clinical trial update evaluating different Venetoclax treatment durations in older adults with newly diagnosed acute myeloid leuke…