Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-02-06Clinical Trial Update: HVA vs IA/DA or VA in the Treatment of ND HR-AML [Phase 3]
A Phase 3 clinical trial comparing HVA regimens against IA/DA or VA regimens for newly diagnosed high-risk acute myeloid leukemia is current…
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CLINICAL_TRIALS research · 2025-01-31Clinical Trial Update: Interferon-alpha As Maintenance Therapy for Favorable-risk Acute Myeloid Leukemia [Phase 3]
This clinical trial update describes a Phase 3 study evaluating interferon-alpha as maintenance therapy in favorable-risk acute myeloid leuk…
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CLINICAL_TRIALS research · 2025-01-30Clinical Trial Update: Molecular Characterization of Patients With Acute Myeloid Leukemia and the Impact of Clonal Evolution in the Response to Therapeutic Treatments
This clinical trial update outlines the molecular characterization of patients with acute myeloid leukemia and investigates how clonal evolu…
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Relation of C-reactive Protein/ Albumin Ratio and Coagulation Profile in Acute Myeloid Leukemia Patients
Assiut University is conducting a clinical study to examine the relationship between the C-reactive protein/albumin ratio and coagulation pa…
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Epidemiology of Infection in Acute Myeloid Leukemia (AML)
This clinical trial update examines the epidemiology of infections in patients with acute myeloid leukemia, and the study is not yet recruit…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: Clinical Study on the Safety and Efficacy of Autologous CD84 Chimeric Antigen Receptor T-Cell Therapy for Adult Relapsed/Refractory Acute Myeloid Leukemia. [EARLY_Phase 1]
An early-phase study is evaluating autologous CD84 CAR-T cell therapy for adults with relapsed or refractory acute myeloid leukemia; the tri…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: Expectations of Patients in Palliative Situation
A clinical trial in acute myeloid leukemia at University Hospital Montpellier is examining patients' expectations in a palliative care setti…
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: First-in-human Study Aiming to Characterize the Safety, Tolerability, Pharmacokinetic and Preliminary Signs of Activity of ABD-3001 in Refractory or Relapsed AML and High Risk MDS Adult Patients [Phase 1, Phase 2]
First-in-human Phase 1/2 study of ABD-3001 to evaluate safety, tolerability, pharmacokinetics, and preliminary activity in adults with refra…
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: Avapritinib Combined With Azacitidine and Venetoclax in the Treatment of Relapsed AML After Allo-HSCT [Phase 2]
Phase 2 clinical trial evaluating the combination of avapritinib with azacitidine and venetoclax for relapsed acute myeloid leukemia after a…
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: NK Cell Infusion for Remission Consolidation in AML: A Phase II Trial [Phase 2]
A Phase II study evaluating natural killer (NK) cell infusion as remission-consolidation therapy for acute myeloid leukemia; the trial is cu…
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CLINICAL_TRIALS research · 2025-01-17Clinical Trial Update: Azacitidine Combined with Donor Lymphocyte Infusion for Acute Myeloid Leukemia Post-transplant Relapse Prevention. [Phase 2]
A Phase 2 clinical trial evaluating azacitidine in combination with donor lymphocyte infusion to prevent relapse of acute myeloid leukemia a…
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CLINICAL_TRIALS research · 2025-01-16Clinical Trial Update: Intermediate-dose HAD Regimen for CEBPA Double-mutated AML [NA]
The document notes an ongoing clinical trial in China evaluating an intermediate-dose HAD regimen for CEBPA double-mutated acute myeloid leu…
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CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: Selinexor Combined With Venetoclax Maintenance Therapy After Allo-HSCT [Phase 2]
Phase 2 clinical trial update evaluating the combination of selinexor and venetoclax as maintenance therapy after allogeneic hematopoietic s…
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CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: Avapritinib Maintenance for AML With KIT Mutations [Phase 2]
Phase 2 trial evaluating maintenance avapritinib in adults with acute myeloid leukemia harboring KIT mutations; the study status is not yet …
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: Liquid Micro-biopsy: a Novel Approach to Study Tumor Microenvironment From the Peripheral Blood
A clinical trial is evaluating a liquid micro-biopsy method from peripheral blood to study the tumor microenvironment. The study targets pat…
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: CLAG+VEN vs CLAG in the Treatment of Relapsed/Refractory AML [Phase 4]
This Phase 4 trial compares CLAG+venetoclax versus CLAG for relapsed/refractory acute myeloid leukemia and is not yet recruiting.
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CLINICAL_TRIALS research · 2025-01-07Clinical Trial Update: A Clinical Study to Explore the Safety and Efficacy of CD33 CAR-T Cell in Relapsed/Refractory Acute Myeloid Leukemia [EARLY_Phase 1]
An early-phase study evaluating the safety and efficacy of CD33-directed CAR-T cells in relapsed or refractory acute myeloid leukemia. The t…
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CLINICAL_TRIALS research · 2025-01-07Clinical Trial Update: Evaluation of the Safety and Efficacy of Human CI-135 (FLT3) Targeted CAR-T Cells Injection for Subjects with Relapsed/Refractory Acute Myeloid Leukemia [EARLY_Phase 1]
This early-phase (Phase 1) clinical trial evaluates the safety and potential efficacy of CI-135, a FLT3-targeted CAR-T cell therapy, for rel…
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CLINICAL_TRIALS research · 2025-01-07Clinical Trial Update: Effect of Donor Chose on the Outcomes of GVHD Prophylaxis Underwent the Combined Treatment of ATG/PTCy for Haplo-HSCT
This clinical trial registry entry describes a study evaluating whether donor selection affects graft-versus-host disease prophylaxis outcom…
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CLINICAL_TRIALS research · 2025-01-06Clinical Trial Update: Venetoclax and Decitabine Assessment in Patients (≥60 - <75 Years) with Newly Diagnosed AML Eligible for Allo-SCT [Phase 2]
Phase 2 trial assessing the combination of venetoclax and decitabine in patients aged 60 to 74 with newly diagnosed acute myeloid leukemia e…
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CLINICAL_TRIALS research · 2025-01-01Clinical Trial Update: Preventing of GVHD with Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Ruxolitinib At Children and Young Adults with Hemoblastosis [Phase 2, Phase 3]
A multi-agent trial in pediatric and young adult patients explores preventing graft-versus-host disease after transplantation using post-tra…
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CLINICAL_TRIALS research · 2024-12-30Clinical Trial Update: Immediate Allogeneic Hematopoietic Stem Cell Transplantation Versus Re-treatment for Patients With High-Risk Acute Myeloid Leukemia [NA]
A clinical trial evaluating immediate allogeneic hematopoietic stem cell transplantation versus re-treatment for patients with high-risk acu…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: NKX101, Intravenous Allogeneic CAR NK Cells, in Adults With AML or MDS [Phase 1]
Nkarta's NKX101 is an intravenous allogeneic CAR-NK cell therapy being studied in adults with relapsed/refractory acute myeloid leukemia and…
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CLINICAL_TRIALS research · 2024-12-24Clinical Trial Update: BN104 in Combination With Chemotherapy or Targeted Agents for Acute Myeloid Leukemia [Phase 1, Phase 2]
This clinical trial update reports a Phase 1/2 study evaluating BN104 in combination with chemotherapy or targeted agents for Acute Myeloid …
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CLINICAL_TRIALS research · 2024-12-20Clinical Trial Update: GvHD Prophylaxis in Unrelated Donor HCT: Randomized Trial Comparing PTCY Versus ATG [Phase 3]
Phase 3 randomized trial comparing post-transplant cyclophosphamide versus anti-thymocyte globulin for graft-versus-host disease prophylaxis…