Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: Genetic Ablation of CD33 in HSC to Broaden the Therapeutic Index of CD33-directed Immunotherapy in Patients with AML [Phase 1]
Phase 1 clinical trial exploring genetic ablation of CD33 in hematopoietic stem cells to broaden the therapeutic index of CD33-directed immu…
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: Study to Evaluate Imetelstat in Patients With High-Risk MDS or AML Failing HMA-based Therapy [Phase 2]
Phase 2 trial evaluating imetelstat in patients with high-risk myelodysplastic syndromes or acute myeloid leukemia after failure of hypometh…
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Comparing Post-Transplant Cyclophosphamide As GVHD Prophylaxis to Standard of Care for Acute Leukemia Patients [Phase 3]
A Phase 3 trial is evaluating post-transplant cyclophosphamide as GVHD prophylaxis versus standard of care in acute leukemia patients in rem…
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Targeting Acute Myeloid Leukemia Immunosuppressive Microenvironment by combinedIDO1 Inhibition and PD-1 Blockade
A clinical trial is evaluating a combination of an IDO1 inhibitor and PD-1 blockade to target the immunosuppressive microenvironment in acut…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Efficacy of Gilteritinib in Combination With FLAI as Induction Therapy of FLT3-positive Acute Myeloid Leukemia [Phase 2]
A Phase 2 clinical trial is evaluating the efficacy of gilteritinib in combination with the FLAI induction regimen for FLT3-mutated acute my…
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CLINICAL_TRIALS research · 2025-03-11Clinical Trial Update: Off-the-shelf CD123 CAR-NK for R/R AML [EARLY_Phase 1]
Early Phase 1 trial evaluating off-the-shelf CD123 CAR-NK cells for relapsed or refractory acute myeloid leukemia; currently recruiting.
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CLINICAL_TRIALS research · 2025-03-10Clinical Trial Update: A Clinical Trial of BP1002 in Patients With Refractory/Relapsed Acute Myeloid Leukemia (AML) [Phase 1]
A Phase 1 clinical trial evaluating BP1002 in patients with refractory or relapsed acute myeloid leukemia is currently recruiting.
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CLINICAL_TRIALS research · 2025-03-10Clinical Trial Update: Study of Oral PCLX-001 in R/R Acute Myeloid Leukemia [Phase 1]
A Phase 1 clinical trial evaluating oral PCLX-001 for relapsed or refractory acute myeloid leukemia is currently recruiting.
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: Clinical Trial of BP1001 in Combination With With Venetoclax Plus Decitabine in AML [Phase 2]
This clinical trial update concerns a Phase 2 study of BP1001 in combination with venetoclax and decitabine for acute myeloid leukemia, whic…
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CLINICAL_TRIALS research · 2025-03-04Clinical Trial Update: A Study of XS-04 in Patients with Relapsed or Refractory Hematologic Malignancies [Phase 1]
Phase 1 study of XS-04 in relapsed or refractory hematologic malignancies, including B-cell lymphoma, acute myeloid leukemia, and myelodyspl…
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CLINICAL_TRIALS research · 2025-03-04Clinical Trial Update: Safely Delivered Targeted High-dose Irradiation Followed by Adoptive Immunotherapy with Regulatory and Conventional T Cells to Increase Potency of Hematopoietic Stem Cell Transplantation in High-risk Acute Leukemia [NA]
This clinical trial update describes testing a treatment strategy that uses targeted high-dose irradiation followed by adoptive immunotherap…
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: Psychometric Properties of the Therapy-Related Symptom Checklist-Children
This clinical trial update evaluates the psychometric properties of the Therapy-Related Symptom Checklist-Children and its use in pediatric …
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: Relation Between Venetoclax Plasma Concentration and Remission in Adults with Acute Myeloid Leukemia (PREDICLAX)
An ongoing clinical trial is investigating whether venetoclax plasma concentration relates to remission outcomes in adults with acute myeloi…
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: Effectiveness of Early Intervention in Palliative Care for Acute Myeloid Leukemia Patients Comparing to Standard of Care [NA]
A Universidade do Porto-led clinical trial is evaluating whether early palliative care intervention improves outcomes for patients with acut…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: PTCy and ATG for MSD and MUD Transplants [Phase 1, Phase 2]
Ongoing Phase 1/2 clinical trial evaluating post-transplant cyclophosphamide and anti-thymocyte globulin for matched sibling and matched unr…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: CD123-CD16-NK Cells Immunotherapy for AML [Phase 1]
Phase 1 clinical trial evaluating CD123-CD16-NK cell immunotherapy for Acute Myeloid Leukemia is currently recruiting.
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Study of Tretinoin Capsules in Combination With Azacitidine and Venetoclax in Treatment Naïve Participants With Acute Myeloid Leukemia [NA]
A planned clinical trial to test the combination of tretinoin capsules with azacitidine and venetoclax in adults with treatment-naïve acute …
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Dose-escalation Study of D-CMG Regimen for the Treatment of Elderly Newly Diagnosed AML Patients [Phase 1]
This clinical trial update announces a phase 1 dose-escalation study evaluating the D-CMG regimen for elderly patients with newly diagnosed …
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Chiglitazar Sodium Combined With Venetoclax and Azacitidine (CVA) for the Treatment of R/R AML [Phase 1]
Phase 1 clinical trial evaluating chiglitazar sodium combined with venetoclax and azacitidine (CVA) for relapsed/refractory acute myeloid le…
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CLINICAL_TRIALS research · 2025-02-21Clinical Trial Update: Cardioprotection in AML [Phase 2]
This clinical trial update describes a Phase 2 study on cardioprotection in acute myeloid leukemia that is currently recruiting. The sponsor…
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CLINICAL_TRIALS research · 2025-02-20Clinical Trial Update: Veneclax, Chidaniline Combined With Azacitidine Followed by Decitabine + MAG Regimen in the Treatment of Elderly Untreated AML [Phase 2]
Phase 2 trial update for elderly patients with untreated acute myeloid leukemia evaluating Veneclax and Chidaniline with Azacitidine, follow…
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: VCA Regimen Followed by D-MAG Regimen on the Treatment of Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia (AML) [Phase 2]
Phase 2 clinical trial evaluating a sequence of the VCA regimen followed by the D-MAG regimen for elderly patients with newly diagnosed acut…
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: Randomized Study of Conditioning of Fludarabine Combined With Single or Dual Alkylating Agents in Myeloid Malignancies [Phase 3]
A Phase 3 randomized trial evaluating conditioning with fludarabine plus single versus dual alkylating agents in myeloid malignancies (acute…
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: Chemotherapy CLAGE-Ven Sequential With Reduced Intensity Conditioning for Refractory Acute Myelodi Leukemia [Phase 2]
Phase 2 clinical trial evaluating sequential chemotherapy CLAGE-Ven with reduced-intensity conditioning for refractory acute myeloid leukemi…
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CLINICAL_TRIALS research · 2025-02-10Clinical Trial Update: Reduced Intensity Conditioning Regimens for Acute Myeloid Leukemia and Myelodysplastic Syndrome [Phase 3]
A Phase 3 clinical trial update evaluating reduced-intensity conditioning regimens for patients with acute myeloid leukemia or myelodysplast…