Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: A Study of HYML-122 and Cytarabine in Patients With FLT3 Positive Relapsed or Refractory Acute Myeloid Leukemia (AML) [Phase 2]
A Phase 2 clinical trial evaluating HYML-122 plus Cytarabine in FLT3-positive relapsed or refractory AML; currently recruiting.
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Breath Analysis for the Detection of Invasive Fungal Infections
This clinical trial update describes a breath analysis approach being studied to detect invasive fungal infections in patients with leukemia…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Micro-transplantation in Elderly Patients With Acute Myeloid Leukemia [NA]
This clinical trial entry notes a study evaluating micro-transplantation in elderly patients with acute myeloid leukemia, currently in the r…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: HEC73543 Versus Salvage Chemotherapy in R/R FLT3-ITD AML [Phase 3]
Phase 3 trial evaluating HEC73543 versus salvage chemotherapy in relapsed/refractory FLT3-ITD acute myeloid leukemia is currently recruiting…
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: Combination Salvage Therapy With Venetoclax and Decitabine in Relapsed/Refractory AML [Phase 2]
Phase 2 clinical trial evaluating salvage therapy with venetoclax and decitabine for relapsed/refractory acute myeloid leukemia. The study a…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML [Phase 3]
Phase 3 trial evaluating Revumenib in combination with azacitidine and venetoclax for adults with NPM1-mutated or KMT2A-rearranged acute mye…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: The Application of CAR-T Cell Therapy in Relapsed and Refractory Malignant Hematologic Tumors [Phase 1, Phase 2]
Ongoing Phase 1/Phase 2 trials are evaluating CAR-T cell therapy for relapsed or refractory malignant hematologic tumors, including aggressi…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Hyperbaric Oxygen Therapy and Allogeneic Peripheral Blood Stem Cell (PBSC) Transplant [EARLY_Phase 1]
An early-phase 1 clinical trial is evaluating hyperbaric oxygen therapy in combination with allogeneic peripheral blood stem cell transplant…
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CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: MIF Involvement in AML
Clinical trial update examining the involvement of macrophage migration inhibitory factor (MIF) in acute myeloid leukemia. The study (NCT039…
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CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: Study of Management and Prognosis of Patients With Acute Myeloblastic Leukemia in Saint-Antoine Hospital
The study at Saint-Antoine Hospital examines management and prognosis of patients with acute myeloid leukemia; it is currently not recruitin…
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CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: Gut Health in Children With Cancer
A clinical trial update indicates that a study on gut health in children with cancer is currently recruiting, enrolling conditions including…
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CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: Selinexor Combined With Azacitidine Therapy in High-Risk Myeloid Neoplasms Patients [Phase 2]
Phase 2 clinical trial evaluating selinexor in combination with azacitidine for high-risk myeloid neoplasms, currently not yet recruiting.
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CLINICAL_TRIALS research · 2025-03-27Clinical Trial Update: Eltanexor and Venetoclax in Relapsed or Refractory Myelodysplastic Syndrome and Acute Myeloid Leukemia [Phase 1]
A Phase 1 study of eltanexor with venetoclax for relapsed or refractory myelodysplastic syndromes and acute myeloid leukemia is currently re…
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: Anti-NKG2A Monoclonal Antibody for AML or MDS Patients Undergoing Haploidentical Transplantation [Phase 2]
Phase 2 clinical trial evaluating an anti-NKG2A monoclonal antibody in Acute Myeloid Leukemia or Myelodysplastic Syndromes patients undergoi…
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: Study Investigating the Efficacy and Safety of the Addition of Oral-azacitidine to Salvage Treatment by Gilteritinib in Subjects ≥18 Years of Age With Relapsed/Refractory FLT3-mutated Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial evaluating the addition of oral azacitidine to gilteritinib salvage therapy in adults with relapsed/refractory FLT3-m…
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: Epidemiological Study of a Prospective Cohort of Patients Aged 60 and Over Managed for Acute Myeloid Leukemia (AML) and Receiving Intensive Induction Therapy
A prospective epidemiological cohort study of patients aged 60 and older with acute myeloid leukemia undergoing intensive induction therapy,…
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: UCMSC-Exo for Chemotherapy-induced Myelosuppression in Acute Myeloid Leukemia [Phase 1]
Phase 1 clinical trial evaluating UCMSC-Exo (umbilical cord mesenchymal stem cell-derived exosomes) to address chemotherapy-induced myelosup…
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: A Study Comparing Treatment Preference Between Oral Decitabine/Cedazuridine and Azacitidine in Myelodysplastic Syndrome, Low-Blast Acute Myeloid Leukemia, or Chronic Myelomonocytic Leukemia [Phase 3]
A Phase 3 trial comparing oral decitabine/cedazuridine with azacitidine in myelodysplastic syndromes, acute myeloid leukemia with low blast …
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Involvement of CDA and/or dCK Metabolizing Enzymes in the Response to Azacytidine Treatment of Patients With Hematologic Malignancies [NA]
A clinical trial update examining whether CDA and/or dCK metabolizing enzymes influence the response to azacitidine in patients with hematol…
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Infusion of Alloreactive nk Cells for Mrd-positive Aml Patients [NA]
A clinical trial is evaluating infusion of alloreactive natural killer (NK) cells in patients with acute myeloid leukemia who have minimal r…
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: Characterization of the Mechanisms of Resistance to Azacitidine
This clinical trial is investigating the mechanisms underlying resistance to azacitidine. It targets patients with myelodysplastic syndromes…
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CLINICAL_TRIALS research · 2025-03-17Clinical Trial Update: A Prospective Randomized Comparison of HDAC Vs AD in the Induction Chemothrapy for AML. [Phase 3]
Phase 3 randomized trial comparing two induction chemotherapy regimens for acute myeloid leukemia (HDAC vs AD), currently enrolling by invit…
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CLINICAL_TRIALS research · 2025-03-17Clinical Trial Update: A Study to Evaluate the STI-8591 in Subjects With Advanced Acute Myeloid Leukemia (AML) [Phase 1]
A Phase 1 clinical trial evaluating STI-8591 in adults with advanced acute myeloid leukemia is currently recruiting.
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CLINICAL_TRIALS research · 2025-03-17Clinical Trial Update: Study to Compare Azacitidine Plus Pevonedistat Versus Azacitidine in Patients With Acute Myeloid Leukemia Not Eligible for Standard Chemotherapy [Phase 3]
Phase 3 clinical trial update comparing azacitidine plus pevonedistat versus azacitidine in patients with acute myeloid leukemia not eligibl…
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CLINICAL_TRIALS research · 2025-03-17Clinical Trial Update: A Single-arm, Prospective Study of TBI + BUMEL As a Conditioning Regimen for Salvage HSCT in Patients with R/R AML [NA]
A single-arm prospective trial evaluating a conditioning regimen of total body irradiation (TBI) plus Busulfan-Melphalan (BUMEL) before salv…