Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Analysis of the Immunobiology of Acute Myeloid Leukemia Relapses After Allogeneic Hematopoietic Stem Cell Transplant (HSCT) for the Generation of Guidelines and Personalized Therapeutic Pathways
This clinical trial update analyzes the immunobiology of acute myeloid leukemia relapses after allogeneic hematopoietic stem cell transplant…
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: APVO436 Phase 1b/2 Study in Patients With Newly Diagnosed AML [Phase 1]
APVO436 is being studied in a Phase 1b/2 trial for newly diagnosed acute myeloid leukemia, with recruitment ongoing for the Phase 1 portion.
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: Conditioning Regimen in Elderly AML Patients Receiving Haplo-HSCT. [NA]
This clinical trial update discusses a conditioning regimen for elderly patients with acute myeloid leukemia undergoing haploidentical hemat…
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CLINICAL_TRIALS research · 2025-05-08Clinical Trial Update: Decoding the Inflammasome Influence on Treatment Response in Acute Myeloid Leukemia
This clinical trial update describes a study investigating how inflammasome signaling influences treatment response in Acute Myeloid Leukemi…
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: Venetoclax and Azacitidine for Non-Elderly Adult Patients With Acute Myeloid Leukemia [Phase 2]
A Phase 2 trial assessing venetoclax in combination with azacitidine for non-elderly adults with acute myeloid leukemia; the study is curren…
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CLINICAL_TRIALS research · 2025-05-06Clinical Trial Update: Registry of Myelodysplastic Syndromes and Therapy-related Acute Myeloid Leukemia
A new clinical trial registry entry for patients with myelodysplastic syndromes and acute myeloid leukemia is currently recruiting.
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CLINICAL_TRIALS research · 2025-05-06Clinical Trial Update: Refining the Role of Mid-induction Bone Marrow Biopsy in Acute Myeloid Leukemia: A Pilot Study
A pilot study at University of Alabama at Birmingham is investigating the role of mid-induction bone marrow biopsy in Acute Myeloid Leukemia…
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: Donor-Derived Ex-Vivo Expanded Natural Killer Cell Infusions in Children and Young Adults With High Risk Acute Myeloid Leukemia Receiving Myeloablative HLA-Haploidentical Hematopoietic Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating donor-derived ex-vivo expanded natural killer cell infusions in pediatric and young adult patients with hi…
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: KIR Favorable Mismatched Haplo Transplant and KIR Polymorphism in ALL/AML/MDS Allo-HCT Children [Phase 2]
This clinical trial update describes a Phase 2 study evaluating KIR-favorable mismatched haploidentical transplantation and KIR polymorphism…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Precision-T: A Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies [Phase 1]
Phase 1 study update for Orca-T in recipients undergoing allogeneic transplantation for hematologic malignancies; the trial is currently act…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Collecting and Storing Tissue From Young Patients With Cancer
A completed clinical trial update from the Children’s Oncology Group describing the collection and storage of tissue from pediatric cancer p…
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CLINICAL_TRIALS research · 2025-05-01Clinical Trial Update: CLAG-GO for Patients With Persistent, Relapsed or Refractory AML [Phase 2]
Phase 2 clinical trial update for the CLAG-GO regimen in adults with persistent, relapsed, or refractory acute myeloid leukemia, currently r…
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CLINICAL_TRIALS research · 2025-04-27Clinical Trial Update: Biomarkers in Patients With Anemia-Induced Thrombocytopenic Bleeding [NA]
This clinical trial update notes ongoing recruitment for a study examining biomarkers in patients with anemia-induced thrombocytopenic bleed…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Total Body Irradiation and Cladribine Before Allogeneic Hematopoietic Cell Transplantation in Patients With AML (Acute Myeloid Leukemia) and Myelodysplastic Syndromes [Phase 2]
A Phase 2 clinical trial is evaluating total body irradiation and cladribine as conditioning before allogeneic hematopoietic cell transplant…
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CLINICAL_TRIALS research · 2025-04-23Clinical Trial Update: Study of REM-422 in Patients With AML or Higher Risk MDS [Phase 1]
Remix Therapeutics is conducting a Phase 1 study of REM-422 in patients with myelodysplastic syndromes and acute myeloid leukemia, including…
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CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: Matched Unrelated vs. Haploidentical Donor for Allogeneic Stem Cell Transplantation in Patients With Acute Leukemia [Phase 2]
This entry describes a Phase 2 clinical trial evaluating matched unrelated donor versus haploidentical donor approaches for allogeneic stem …
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CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: A Study to Asses Effectiveness and Treatment Management of Oral Venetoclax Tablets + Subcutaneously Injected Azacitidine in Adult Participants Ineligible for Intensive Chemotherapy With de Novo Acute Myeloid Leukemia (AML) in Italy
An ongoing Italy-based study evaluating oral venetoclax plus subcutaneous azacitidine in adults with de novo acute myeloid leukemia who are …
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CLINICAL_TRIALS research · 2025-04-17Clinical Trial Update: Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST) Trial [Phase 2]
Phase 2 trial evaluating fecal microbiota transplantation before allogeneic stem cell transplant; recruitment is ongoing across multiple hem…
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CLINICAL_TRIALS research · 2025-04-17Clinical Trial Update: Phase I Clinical Study: BG1805 Injection in the Treatment of Relapsed or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
This entry notes an ongoing Phase I/II clinical trial, currently recruiting, evaluating BG1805 injection for relapsed or refractory acute my…
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CLINICAL_TRIALS research · 2025-04-17Clinical Trial Update: Cusatuzumab in Combination With Background Therapy for the Treatment of Participants With Acute Myeloid Leukemia [Phase 1]
Phase 1 clinical trial evaluating cusatuzumab in combination with background therapy for acute myeloid leukemia. The study is currently acti…
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CLINICAL_TRIALS research · 2025-04-15Clinical Trial Update: Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT) [Phase 1]
Phase 1 clinical trial assessing a preventive therapy to reduce graft-versus-host disease in participants with hematologic malignancies unde…
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CLINICAL_TRIALS research · 2025-04-13Clinical Trial Update: A Phase Ⅰb/Ⅱ Clinical Study of Clifutinib Besylate Combined With Chemotherapy in the Treatment of Newly Diagnosed AML [Phase 1, Phase 2]
A Phase Ⅰb/Ⅱ clinical trial evaluating clifutinib besylate in combination with chemotherapy for newly diagnosed acute myeloid leukemia is cu…
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CLINICAL_TRIALS research · 2025-04-13Clinical Trial Update: Safety and Efficacy of RVU120 Combined With Venetoclax for Treatment of Relapsed/Refractory AML [Phase 2]
Ongoing Phase 2 study evaluating the safety and efficacy of RVU120 in combination with venetoclax for relapsed/refractory acute myeloid leuk…
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: An Open-label Phase 3b Study of Ivosidenib in Combination With Azacitidine in Adult Patients Newly Diagnosed With IDH1m Acute Myeloid Leukemia (AML) Ineligible for Intensive Induction Chemotherapy. [Phase 3]
Open-label Phase 3b trial of ivosidenib plus azacitidine in IDH1-mutant acute myeloid leukemia patients ineligible for intensive chemotherap…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Single Cell Acute Leukemia Analysis [NA]
This clinical trial update describes a study on single-cell analysis in acute myeloid leukemia, which is not yet recruiting.