Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation [Phase 1]
This Phase 1 trial update discusses orally administered AG-120 (ivosidenib) for IDH1-mutated hematologic malignancies, including relapsed/re…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: a New Treatment of Newly Diagnosed IDH1 Mutation Acute Myeloid Leukemia [Phase 2]
This clinical trial update describes a Phase 2 study evaluating a new treatment for newly diagnosed IDH1-mutant acute myeloid leukemia and i…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Vaccination Against Human Papillomavirus (HPV) After Allogeneic Stem Cell Transplantation [Phase 2]
This Phase 2 trial investigates HPV vaccination in recipients of allogeneic stem cell transplantation and is currently recruiting.
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: ABBA CORD: dCBT w/ Abatacept for aGVHD Prophylaxis [Phase 2]
A Phase 2 trial (ABBA CORD) evaluating donor-derived cord blood T cells with abatacept for prophylaxis of acute graft-versus-host disease in…
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Multi-institutional Prospective Research of Expanded Multi-antigen Specifically Oriented Lymphocytes for the Treatment of VEry High Risk Hematopoietic Malignancies [Phase 1]
This is a Phase 1, multi-institutional trial evaluating expanded multi-antigen oriented lymphocytes for very high-risk hematologic malignanc…
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Intensive Therapy Combined With Venetoclax for Adult Acute Myeloid Leukemia [Phase 2, Phase 3]
Clinical trial evaluating intensive therapy combined with venetoclax for adult acute myeloid leukemia is currently active but not recruiting…
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Emapalumab With Post-Transplant Cyclophosphamide, Tacrolimus and Mycophenolate Mofetil for the Prevention of Graft-versus-Host Disease After Donor Reduced-Intensity Hematopoietic Cell Transplant [Phase 1]
Phase 1 trial evaluating emapalumab with post-transplant cyclophosphamide, tacrolimus and mycophenolate mofetil to prevent graft-versus-host…
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: HAV Versus DAV/IAV Induction Regimen in Elderly Patients With AML [Phase 2]
Phase 2 clinical trial update comparing HAV versus DAV/IAV induction regimens in elderly patients with acute myeloid leukemia.
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Adding Itacitinib to Cyclophosphamide and Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Hematopoietic Stem Cell Transplants [Phase 2]
Phase 2 clinical trial update describing the addition of itacitinib to cyclophosphamide and tacrolimus for preventing graft-versus-host dise…
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Efficacy and Safety of ATO Plus ATRA in Nucleophosmin-1 Mutated Acute Myeloid Leukemia [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the combination of arsenic trioxide (ATO) and all-trans retinoic acid (ATRA) in patients with NPM1-…
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Efficacy of Intermediate-Dose Cytarabine Induction Regimen in Adult AML [Phase 3]
A Phase 3 trial is evaluating whether an intermediate-dose cytarabine induction regimen improves outcomes in adults with acute myeloid leuke…
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: A Study of c-Kit Mutation as MRD in Acute Myeloid Leukemia
A clinical trial exploring c-KIT mutation as minimal residual disease (MRD) in acute myeloid leukemia. It is currently recruiting.
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Optimizing Induction Chemotherapy Regimens for ND Elderly AML Patients Who Are Eligible for Intense Chemotherapy [NA]
Clinical trial update showing ongoing recruitment to optimize induction chemotherapy regimens for newly diagnosed elderly patients with acut…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: Gilteritinib in Combination With Venetoclax and Azacitidine for AML Patients With FLT3 Mutations Ineligible for Intensive Treatment [Phase 2]
A Phase 2 trial is evaluating gilteritinib in combination with venetoclax and azacitidine for FLT3-mutated acute myeloid leukemia patients i…
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: Study of Tagraxofusp for Post-Transplant Maintenance for Patients With CD 123+ AML, MDS, MF and CMML (HSCT 002) [Phase 1]
An early-phase clinical trial evaluating Tagraxofusp as post-transplant maintenance in patients with CD123-positive acute myeloid leukemia, …
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: A Phase 1 Study With LYT-200 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML), or With Relapsed/Refractory, High-risk Myelodysplastic Syndrome (MDS) [Phase 1]
Phase 1 study evaluating LYT-200 in adults with relapsed/refractory acute myeloid leukemia or relapsed/refractory high-risk myelodysplastic …
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: XP-005 Personalized Vaccine Alone or in Combination With Toripalimab for the Prevention of Relapse After Remission in Acute Myeloid Leukemia [EARLY_Phase 1]
This early-phase 1 trial update covers XP-005, a personalized cancer vaccine used alone or in combination with toripalimab for preventing re…
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: Thiotepa Combined With Busulfan and Fludarabine Conditioning Regimen for Haploidentical Hematopoietic Stem Cell Transplantation in Elderly Patients With High-Risk Acute Myeloid Leukemia [Phase 2]
A Phase 2 clinical trial is evaluating a conditioning regimen combining thiotepa, busulfan, and fludarabine for haploidentical hematopoietic…
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: A Study of CFI-400945 With or Without Azacitidine in Patients With AML, MDS or CMML [Phase 1, Phase 2]
Clinical trial update showing CFI-400945 with or without azacitidine is being studied in acute myeloid leukemia, myelodysplastic syndromes, …
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: Molecular Genetics Guide the Maintenance Therapy After Allogeneic Hematopoietic Stem Cell Transplantation [Phase 2, Phase 3]
Phase 2/Phase 3 clinical trial investigating molecular genetics-guided maintenance therapy after allogeneic hematopoietic stem cell transpla…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Pharmacoscopy-guided Clinical Standard-of-care in r/r AML [Phase 2]
Phase 2 trial evaluating pharmacoscopy-guided standard-of-care for relapsed/refractory acute myeloid leukemia is currently recruiting.
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Palliative Care Oncology in Patients With Relapsed, Refractory, and High-Risk Leukemias or MDS [Phase 2]
This clinical trial update describes a Phase 2 study evaluating palliative care oncology in adults with relapsed, refractory, or high-risk a…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Phase 1 Study of Allo-RevCAR01-T-CD123 in Patients With Selected CD123 Positive Hematologic Malignancies [Phase 1]
Phase 1 study evaluating Allo-RevCAR01-T-CD123 in CD123-positive hematologic malignancies, including relapsed or refractory acute myeloid le…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: IDH Targeted/Non- Targeted vs Non-targeted/IDH-targeted Approaches in the Treatment of Newly Diagnosed IDH Mutated AML Patients Not Candidates for Intensive Induction Therapy (I- DATA Study) [Phase 2]
A Phase 2 clinical trial (I- DATA Study) compares IDH-targeted versus non-targeted treatment approaches in newly diagnosed IDH-mutated acute…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Daunorubicin + Cytarabine + Venetoclax in de Novo AML [NA]
This entry notes a clinical trial evaluating daunorubicin, cytarabine, and venetoclax in newly diagnosed acute myeloid leukemia, with enroll…