Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy [Phase 1]
Phase 1 study evaluating talazoparib in combination with chemotherapy in relapsed pediatric acute myeloid leukemia to assess safety and prel…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Evaluation of Tranexamic Acid in Myelodysplastic Syndromes and Acute Myeloid Leukemia [Phase 2]
A Phase 2 clinical trial is evaluating tranexamic acid in patients with myelodysplastic syndromes and acute myeloid leukemia and is currentl…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial) [Phase 2]
A Phase 2 clinical trial (MyeloMATCH) is evaluating new treatments for newly diagnosed acute myeloid leukemia with an IDH2 gene mutation; th…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Evaluation of Antibiotic Prophylaxis in Myelodysplastic Syndromes and Acute Myeloid Leukemia (MYELO-CAN:ABX) [Phase 2]
This Phase 2 trial from the University of Manitoba is evaluating antibiotic prophylaxis in patients with myelodysplastic syndrome and acute …
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia [Phase 2]
This clinical trial update describes a Phase 2 study of revumenib in combination with chemotherapy for relapsed or refractory leukemia, with…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
First-in-human study of ziftomenib in relapsed or refractory acute myeloid leukemia is underway in Phase 1/Phase 2 trials and is currently r…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Biology Studies of Hematologic Cancers
The document reports an NCI-sponsored biology-focused clinical trial update in hematologic cancers, with enrollment by invitation for condit…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Clinical AML Registry and Biomaterial Database of the Study Alliance Leukemia (SAL)
This ClinicalTrials.gov entry describes the SAL AML registry and biomaterial database. It is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Phase III Study of Induction and Consolidation Chemotherapy With Venetoclax in Patients With Newly Diagnosed AML or MDS-EB-2 [Phase 3]
A Phase III clinical trial is investigating induction and consolidation chemotherapy with venetoclax for newly diagnosed acute myeloid leuke…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Navitoclax, Venetoclax, and Decitabine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Previously Treated With Venetoclax [Phase 1]
This clinical trial update reports a Phase 1 study evaluating a triplet regimen of Navitoclax, Venetoclax, and Decitabine for relapsed or re…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Azacitidine + Venetoclax VS Azacitidineas Maintenance Therapy in AML [Phase 3]
Phase 3 clinical trial comparing azacitidine plus venetoclax to azacitidine maintenance therapy in acute myeloid leukemia; the study is not …
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy [Phase 1]
This clinical trial aims to determine the highest tolerated dose of imetelstat when given with fludarabine and cytarabine in children with r…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A First in Human Study of AUR 103 Calcium to Evaluate Safety, Pharmacokinetics and Pharmacodynamics [Phase 1]
First-in-human Phase 1 study of AUR 103 Calcium to evaluate safety, pharmacokinetics, and pharmacodynamics in adults with acute myeloid leuk…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Venetoclax and CLAG-M for the Treatment of Acute Myeloid Leukemia and High-Grade Myeloid Neoplasms [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating venetoclax in combination with the CLAG-M chemotherapy regimen for acute myeloid leukemia and re…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Leukemia Stem Cell-based Assay to Predict Relapse and Survival in Patients With Acute Myeloid Leukemia
This clinical trial update describes a study evaluating a Leukemia Stem Cell-based assay to predict relapse and survival in patients with Ac…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: TACrolimus Targeted Immunosuppression Cessation in ALlogeneic HCT [Phase 1]
Stanford is conducting a Phase 1 study evaluating cessation of tacrolimus immunosuppression after allogeneic hematopoietic cell transplantat…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Venetoclax, Cladribine, Low Dose Cytarabine, and Azacitidine in Treating Patients With Previously Untreated Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial evaluating a four-drug combination (venetoclax, cladribine, low-dose cytarabine, and azacitidine) for previously untr…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: PET/MRI, 18F-FDG PET/CT and Whole Body MRI in Finding Extramedullary Myeloid Leukemia in Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 1]
An MD Anderson trial is evaluating PET/MRI, 18F-FDG PET/CT, and whole-body MRI to detect extramedullary myeloid leukemia in patients with ne…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: VEN+IDAC vs IDAC in AML [Phase 2, Phase 3]
A Phase 2/3 trial comparing venetoclax plus IDAC versus IDAC alone in acute myeloid leukemia is currently enrolling by invitation.
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Proton-Based Total Marrow Irradiation for Allogeneic Transplantation in High-Risk AML/MDS [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating proton-based total marrow irradiation as conditioning before allogeneic stem cell transplantation in p…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Biological, Prospective Study Evaluating the Dosage of Plasma Cytokines Including the FLT3 Ligand and IL6 of Patients Treated With Non-intensive Chemotherapy
This clinical trial aims to prospectively evaluate plasma cytokine levels, including FLT3 ligand and IL-6, in patients with acute myeloid le…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Azacitidine, Venetoclax, and Gilteritinib in Treating Patients With Recurrent/Refractory FLT3-Mutated Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, or High-Risk Myelodysplastic Syndrome/Myeloproliferative Neoplasm [Phase 1, Phase 2]
This update describes a Phase 1/2 clinical trial evaluating a triplet regimen of azacitidine, venetoclax, and gilteritinib in patients with …
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: MB-dNPM1-TCR.1 in Relapsed/Refractory AML [Phase 1, Phase 2]
Miltenyi Biomedicine is conducting early-phase (Phase 1/2) trials of MB-dNPM1-TCR.1 for relapsed/refractory acute myeloid leukemia, and the …
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Venetoclax, Azacitidine and Liposomal Mitoxantrone for Newly Diagnosed AML [NA]
Clinical trial update for a newly diagnosed acute myeloid leukemia study combining venetoclax, azacitidine, and liposomal mitoxantrone; the …
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: MT2025-35 Allogeneic Hematopoietic Stem Cell Transplantation Using Reduced Intensity Conditioning Treosulfan and Fludarabine, With Post-Transplant Cytoxan (PTCy) for the Treatment of Hematological Diseases [Phase 2]
Phase 2 trial evaluating allogeneic hematopoietic stem cell transplantation with reduced-intensity conditioning using treosulfan and fludara…