Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome [Phase 1]
Phase 1 clinical trial evaluating BH-30236 in patients with relapsed or refractory acute myeloid leukemia and higher-risk myelodysplastic sy…
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: NTX-301 in MDS/AML [Phase 1]
Phase 1 clinical trial update for NTX-301 in acute myeloid leukemia and myelodysplastic syndromes, including chronic myelomonocytic leukemia…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Chimeric Antigen Receptor T-cells for The Treatment of AML Expressing CLL-1 Antigen [Phase 1]
Phase 1 clinical trial evaluating CAR-T cells targeting CLL-1 (CLEC12A) for acute myeloid leukemia; the study is active but not recruiting.
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Venetoclax + Azacitidine in Patients With Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial update for venetoclax plus azacitidine in acute myeloid leukemia, currently recruiting.
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Venetoclax-Enhanced BUCY vs. Standard BUCY Conditioning in High-Risk AML and MDS Patients Undergoing Allo-HSCT (Ven-BUCY Study) [NA]
A clinical trial evaluating the addition of venetoclax to busulfan/cyclophosphamide conditioning for high-risk acute myeloid leukemia and my…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: An Adaptive Open-label Multicentre Phase 1/2 Trial, to Determine the Recommended Phase 2 Dose of CCTx-001, and to Assess Safety, Tolerability, and Clinical Activity in Patients With Relapsed/Refractory Acute Myeloid Leukaemia [Phase 1, Phase 2]
Adaptive open-label Phase 1/2 trial to determine the recommended Phase 2 dose of CCTx-001 and evaluate safety, tolerability, and clinical ac…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: BSB-1001 in Patients Undergoing HLA-Matched Allogenic Hematopoietic Stem Cell Transplant for AML, ALL or MDS [Phase 1, Phase 2]
Update on a Phase 1/2 trial of BSB-1001 in patients undergoing HLA-matched allogeneic hematopoietic stem cell transplantation for acute myel…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Monitoring Minimal Residual Disease of Patients With Acute Myelogenous Leukemia or High Grade Myelodysplastic Syndrome
An ongoing University of Rochester clinical trial investigates monitoring minimal residual disease in patients with acute myeloid leukemia o…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia and Persistent/Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm [Phase 1]
This document describes an ongoing Phase 1 clinical trial evaluating a genetically modified T-cell immunotherapy for adults with relapsed/re…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Mitoxantrone Hydrochloride Liposome, Standard-dose of Cytarabine and Venetoclax in the Treatment of R/R AML [Phase 2]
Phase 2 clinical trial evaluating liposomal mitoxantrone in combination with cytarabine and venetoclax for relapsed/refractory acute myeloid…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Venetoclax Combining Chidamide and Azacitidine (VCA) in the Treatment of R/R AML [Phase 2]
Phase 2 clinical trial evaluating venetoclax in combination with chidamide and azacitidine (VCA) for relapsed/refractory acute myeloid leuke…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: A Study Comparing Venetoclax and Azacitidine Plus Cusatuzumab to Venetoclax and Azacitidine in Newly Diagnosed AML Ineligible for Intensive Therapy [Phase 2]
This is a Phase 2 trial comparing venetoclax and azacitidine plus cusatuzumab versus venetoclax and azacitidine in newly diagnosed acute mye…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: A Long Term Follow-up Study of TScan TCR-T Products
This clinical trial update describes a long-term follow-up study of TScan Therapeutics' TCR-T cell therapies for acute myeloid leukemia, acu…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Leptin: A Marker for AML Chemo-Sensitivity
The trial assesses whether leptin can serve as a biomarker for chemotherapy sensitivity in adults with acute myeloid leukemia, and the study…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Combination of Midostaurin and Gemtuzumab Ozogamicin in First-line Standard Therapy for Acute Myeloid Leukemia (MOSAIC) [Phase 1, Phase 2]
A Phase 1/2 trial (MOSAIC) is evaluating the combination of midostaurin and gemtuzumab ozogamicin as part of first-line therapy for acute my…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Cord Blood Transplant in Adults With Blood Cancers [Phase 2]
Phase 2 trial evaluating cord blood transplant in adults with blood cancers is currently recruiting. Conditions include acute myeloid leukem…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Vyxeos® With Clofarabine for Pediatric AML [Phase 1]
Phase 1 trial update of Vyxeos with Clofarabine for relapsed or refractory pediatric acute myeloid leukemia; study currently recruiting.
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: A Post-treatment Program to Identify and Manage Complications Related to Oncology or Hematology Treatments in Cancer Survivors. [NA]
This clinical trial update describes a post-treatment program to identify and manage complications related to oncology or hematology treatme…
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: A Modified Dose of Rabbit Anti-thymocyte Globulin (rATG) in Children and Adults Receiving Treatment to Help Prepare Their Bodies for a Bone Marrow Transplant [Phase 2]
The update describes a Phase 2 study of a modified dose of rabbit anti-thymocyte globulin (rATG) used to condition patients (children and ad…
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Study of A Venetoclax-based, Anthracycline-free Regimen in Newly Diagnosed CBFβ::MYH11(+) AML [Phase 2]
A Phase 2 clinical trial evaluating a venetoclax-based, anthracycline-free regimen for newly diagnosed CBFB-MYH11-positive acute myeloid leu…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Evaluation of Treosulfan Versus Melphalan Conditioning Followed by PTCy in Patients With AML and MDS Undergoing Allogeneic Transplantation [Phase 2]
Phase 2 clinical trial evaluating treosulfan versus melphalan conditioning followed by post-transplant cyclophosphamide in AML and MDS patie…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: uCD7 CART for Relapsed or Refractory CD7 Positive Hematologic Malignancies [Phase 1]
Phase 1 clinical trial evaluating uCD7 CAR-T cells for relapsed or refractory CD7-positive hematologic malignancies is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: DFP-10917 in Combination With Venetoclax in Relapsed or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating DFP-10917 in combination with venetoclax for relapsed or refractory acute myeloid leukemia is currentl…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Harmonized Clinical and Biological Database for Integrated Research Into the Management of Pediatric Acute Myeloid Leukemia
A harmonized clinical and biological database project to advance research into the management of pediatric acute myeloid leukemia; status is…
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: Expression Pattern and Possible Clinical Significance of CD81 In Myeloid Leukemia
This clinical trial update investigates CD81 expression in acute myeloid leukemia and chronic myeloid leukemia and explores its potential cl…