Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: PLAT-08: A Study Of SC-DARIC33 CAR T Cells In Pediatric And Young Adults With Relapsed Or Refractory CD33+ AML [Phase 1]
A Phase 1 study evaluating SC-DARIC33 CAR T cells in pediatric and young adult patients with relapsed or refractory CD33-positive acute myel…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome [Phase 3]
A Phase 3 clinical trial comparing mismatched related donor versus matched unrelated donor stem cell transplantation in children, adolescent…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: 211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute Leukemia [Phase 1, Phase 2]
Clinical trial update for 211At-BC8-B10 given before donor stem cell transplant in high-risk acute myeloid leukemia, acute lymphoblastic leu…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Cladribine Venetoclax in Monocytic AML [Phase 2]
A Phase 2 clinical trial evaluating the combination of cladribine and venetoclax for monocytic acute myeloid leukemia, currently recruiting.
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies [Phase 1, Phase 2]
A Phase 1/2 study is evaluating CCS1477 (Inobrodib) in multiple hematologic malignancies and is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome [Phase 1, Phase 2]
A phase 1/2 clinical trial at MD Anderson is evaluating a quadruplet regimen of cladribine, idarubicin, cytarabine, and quizartinib for newl…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Study of Biomarker-Based Treatment of Acute Myeloid Leukemia [Phase 1, Phase 2]
A biomarker-based treatment approach for acute myeloid leukemia is being studied in Phase 1/2 trials and the study is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Safety of MT-401-OTS in Patients With Relapsed AML or MDS [Phase 1]
A Phase 1 clinical trial update assessing the safety of MT-401-OTS in patients with relapsed acute myeloid leukemia or myelodysplastic syndr…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Study of NK Cells in the Monitoring of Patients With Acute Leukemia or Myelodysplasia
An update on a clinical trial evaluating natural killer cell therapy for monitoring patients with acute myeloid leukemia, acute lymphoblasti…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Chimeric Antigen Receptor Treatment Targeting CD70 (SEVENTY) [Phase 1]
Phase 1 study of a CD70-targeted chimeric antigen receptor (CAR) T-cell therapy named SEVENTY for acute leukemias; the trial is not yet recr…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Home Blood Transfusions [NA]
Thomas Jefferson University is recruiting for a clinical trial on home blood transfusions. The study targets patients with hematologic malig…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Sorafenib, Busulfan and Fludarabine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia Undergoing Donor Stem Cell Transplant [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating a combination of sorafenib, busulfan, and fludarabine as conditioning therapy for patients with recurr…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Characterization of T-cell Repertoire in Patients With Acute Myeloid Leukemia Undergoing Donor Stem Cell Transplant
This clinical trial study characterizes the T-cell repertoire in patients with acute myeloid leukemia undergoing donor stem cell transplant …
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: SupCD7 CART for Relapsed or Refractory CD7 Positive Hematologic Malignancies [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating SupCD7 CAR T-cell therapy for relapsed or refractory CD7-positive hematologic malignancies is cu…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Study of Individuals and Families With Aberrations in DDX41 or Similar Cancer Predisposition Variants
Clinical trial sponsored by the National Cancer Institute studying individuals and families with DDX41 or similar cancer predisposition vari…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS [Phase 1, Phase 2]
This document reports an ongoing Phase 1/Phase 2 clinical trial of ARD103 CAR-T therapy for relapsed/refractory acute myeloid leukemia and m…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: PTX3-targeted Antifungal Prophylaxis [NA]
A clinical trial is recruiting to evaluate PTX3-targeted antifungal prophylaxis for preventing candidiasis and other fungal infections, incl…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Quality of Life Model for Older Patients With AML
Clinical trial update describing development of a quality-of-life model for older adults with acute myeloid leukemia, sponsored by H. Lee Mo…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: An Efficacy and Safety Study of Oral Azacitidine (CC-486) as Maintenance Therapy in Chinese Participants With Acute Myeloid Leukemia in Complete Remission [Phase 2]
A Phase 2 trial evaluating oral azacitidine (CC-486) as maintenance therapy for Chinese participants with acute myeloid leukemia in complete…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Automated vs Manual Flow-cytometry Gating for Measurable Residual Disease in Acute Myeloid Leukaemia (DUALFLOW)
Clinical trial evaluating automated versus manual flow-cytometry gating for measurable residual disease in adults with acute myeloid leukemi…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Muscle Dysfunction in Patients With Hematological Diseases Referred to Stem Cell Transplant
An ongoing clinical trial investigating muscle dysfunction in patients with hematologic diseases referred for stem cell transplantation.
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: A Long-term Follow-up Study of Patients With ARD103 CAR-T Cell Therapies
This document reports a long-term follow-up study of patients treated with ARD103 CAR-T cell therapy for acute myeloid leukemia (relapsed or…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Study of Families With an Hemopathies Predisposition Related to the DDX41 Gene. [NA]
A clinical trial update describing families with a hematopathy predisposition related to the DDX41 gene mutation. The study is currently rec…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Evaluation of Combined Sensitising and Hypomethylating Therapy Outcomes in AML PDX
A recruiting clinical trial evaluating a combined sensitising and hypomethylating therapy for acute myeloid leukemia using patient-derived x…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Vyxeos Plus Gilteritinib in Relapsed or Refractory, FLT3-Mutated AML [Phase 1]
This update describes an ongoing Phase 1 study evaluating Vyxeos plus gilteritinib for relapsed or refractory FLT3-mutated acute myeloid leu…