Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: AZA + Venetoclax as Maintenance Therapy in Patients With AML in Remission [Phase 2]
Phase 2 clinical trial evaluating azacitidine plus venetoclax as maintenance therapy in patients with acute myeloid leukemia in remission, i…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: A Study of MGD024 in Patients With Relapsed or Refractory Hematologic Malignancies [Phase 1]
MacroGenics reports a Phase 1 study of MGD024 in relapsed or refractory hematologic malignancies is currently recruiting across multiple dis…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: CART123 T Cells in Relapsed or Refractory CD123+ Hematologic Malignancies: A Dose Escalation Phase I Trial [EARLY_Phase 1]
This update describes an early-phase dose-escalation trial evaluating CART123 T cells in relapsed or refractory CD123+ hematologic malignanc…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Niclosamide in Pediatric Patients With Relapsed and Refractory AML [Phase 1]
A Phase 1 clinical trial evaluating niclosamide in pediatric patients with relapsed or refractory acute myeloid leukemia is currently recrui…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome [Phase 1, Phase 2]
A Phase 1/2 clinical trial at MD Anderson evaluating a triple combination of Quizartinib, Decitabine, and Venetoclax for untreated or relaps…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Study to Assess Adverse Events and Change in Disease Activity of Oral Venetoclax in Combination With Subcutaneous (SC) or Intravenous (IV) Azacitidine in Newly Diagnosed Adult Participants With Acute Myeloid Leukemia (AML) Who Are Ineligible for Standard Induction Therapy in India [Phase 4]
Phase 4 clinical trial evaluating safety and changes in disease activity for oral venetoclax in combination with azacitidine (SC or IV) in n…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: FH-FOLR1 Chimeric Antigen Receptor T Cell Therapy for Treating Pediatric Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
Phase 1 clinical trial update evaluating FH-FOLR1 CAR T-cell therapy in pediatric patients with relapsed or refractory acute myeloid leukemi…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: A First-in-Human, JAB-8263 in Adult Patients With Advanced Tumors [Phase 1, Phase 2]
A first-in-human Phase 1/2 trial of JAB-8263 in adults with advanced tumors is currently recruiting across multiple cancer types including l…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Pharmacokinetic and Safety Study of MRX-2843 in Adolescents and Adults With Relapsed/Refractory AML, ALL, or MPAL [Phase 1]
Phase 1 pharmacokinetic and safety study of MRX-2843 in adolescents and adults with relapsed/refractory acute myeloid leukemia, acute lympho…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Venetoclax Plus Intensive Chemotherapy in AML and Advanced MDS [Phase 1]
Phase 1 clinical trial evaluating Venetoclax in combination with intensive chemotherapy for acute myeloid leukemia and advanced myelodysplas…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Venetoclax and Bomedemstat in Patients With Relapsed/Refractory Acute Myeloid Leukemia [Phase 1]
This Phase 1 trial is evaluating the combination of venetoclax and bomedemstat in patients with relapsed or refractory acute myeloid leukemi…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Hu8F4 in Treating Patients With Advanced Hematologic Malignancies [Phase 1]
Hu8F4 is being studied in a Phase 1 trial for multiple advanced hematologic malignancies; the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Pre-DLI or Pro-DLI in Relapsed/Refractory Myeloid Neoplasms After HSCT [NA]
This clinical trial (NCT07319793) sponsored by Peking University People's Hospital is evaluating pre-DLI or pro-DLI approaches in relapsed o…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: A Phase 2 Study of Gemtuzumab Ozogamicin (GO)-Gilteritinib Combination in Adults With FLT3-ITD and/or FLT3-TKD Relapse/Refractory (R/R) AML [Phase 2]
Phase 2 study evaluating the combination of gemtuzumab ozogamicin and gilteritinib in adults with relapsed/refractory FLT3-mutant acute myel…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: High-Intensity Parent Intervention Program in Improving Learning and School Functioning in Latino Children With Acute Leukemia or Lymphoblastic Lymphoma [NA]
This clinical trial update describes a non-pharmacologic High-Intensity Parent Intervention Program aimed at improving learning and school f…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Registry Study on Patient Characteristics, Biological Disease Profile and Clinical Outcome in Acute Myeloid Leukemia and Related Neoplasms - The Biology and Outcome (BiO)-Project
A registry-based study (Biology and Outcome Project) enrolling patients with acute myeloid leukemia and myelodysplastic syndromes/AML to cha…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantation [Phase 1]
Phase 1 clinical trial evaluating preemptive CIML NK cell therapy after hematopoietic stem cell transplantation in patients with acute myelo…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Evaluate the Safety, Tolerability, Pharmacokinetic Profile, Efficacy of Bl-M11D1 [Phase 1]
Phase 1 clinical trial evaluating the safety, tolerability, pharmacokinetics, and preliminary efficacy of Bl-M11D1 in patients with relapsed…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Using Multiparametric Flow Cytometry to Detect Peripheral Blood and Bone Marrow Leukaemia Stem Cells for Relapse Prediction in P-AML
Recruiting study evaluating multiparametric flow cytometry to detect leukemia stem cells in peripheral blood and bone marrow to predict rela…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated or Spliceosome Mutated Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
A Phase 1 dose-escalation and expansion study is evaluating ZE46-0134 in adults with FLT3-mutated or spliceosome-mutated relapsed/refractory…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Safety and Feasibility of Sulforaphane to Promote Early Haematopoietic Recovery After Cord Blood Transplantation [NA]
A clinical trial is evaluating the safety and feasibility of sulforaphane to promote early hematopoietic recovery after cord blood transplan…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: CAV Regimen for R/R AML [Phase 2]
A Phase 2 clinical trial evaluating the CAV regimen for relapsed/refractory acute myeloid leukemia is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: A Study to Assess Adverse Events and How Intravenous (IV) Pivekimab Sunirine Moves Through the Body in Pediatric Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) [Phase 1]
Phase 1 study to evaluate adverse events and pharmacokinetics of intravenously delivered pivekimab sunirine in pediatric patients with relap…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Post-transplantation Maintenance Therapy With Cidabenamide in Patients With Intermediate/High-risk AML [Phase 2]
A Phase 2 trial is evaluating cidabenamide as maintenance therapy after allogeneic hematopoietic cell transplantation in patients with inter…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Cytokine Induced Memory-like NK Cell Adoptive Therapy After Haploidentical Donor Hematopoietic Cell Transplantation [Phase 2]
Phase 2 trial of cytokine-induced memory-like NK cell adoptive therapy after haploidentical donor stem cell transplantation for acute myeloi…