Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances [Phase 1, Phase 2]
A Phase I/II clinical trial evaluating CAR.70, engineered IL-15-transduced cord blood-derived natural killer (NK) cells, in combination with…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Efficacy and Safety of Autologous Peptide-induced Active Immunity in AML Maintenance Therapy [Phase 1]
A Phase 1 clinical trial is evaluating autologous peptide-induced active immunity as maintenance therapy for acute myeloid leukemia and is c…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Stem Cell Transplantation for Participants With Germline RUNX1 Associated Blood Cancers [Phase 2]
Phase 2 clinical trial update describing stem cell transplantation for participants with germline RUNX1-associated blood cancers; the trial …
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial) [Phase 2]
Phase 2 clinical trial evaluating venetoclax with a hypomethylating agent in older or unfit adults with FLT3-mutated acute myeloid leukemia;…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Liposomal Cytarabine and Daunorubicin (CPX-351) and Quizartinib for the Treatment of Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome [Phase 1, Phase 2]
A phase 1/2 clinical trial is evaluating the combination of CPX-351 (liposomal cytarabine and daunorubicin) with Quizartinib for acute myelo…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Mocravimod as Adjunctive and Maintenance Treatment in AML Patients Undergoing Allo-HCT [Phase 3]
Phase 3 clinical trial evaluating mocravimod as adjunctive and maintenance therapy for adults with acute myeloid leukemia undergoing allogen…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Expanded Access Program (EAP) for Galinpepimut-S (GPS) in Patients Diagnosed With AML or MDS
This document notes an expanded access program for Galinpepimut-S (GPS) in patients with acute myeloid leukemia or myelodysplastic syndromes…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression [Phase 1, Phase 2]
AstraZeneca is evaluating AZD3632 as monotherapy or with other anticancer agents in adults with advanced hematologic malignancies associated…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: ALLG AMLM26 INTERCEPT (Investigating Novel Therapy to Target Early Relapse and Clonal Evolution as Pre-emptive Therapy in AML): A Multi-arm, Precision-based, Recursive, Platform Trial [Phase 1, Phase 2]
This entry covers ALLG AMLM26 INTERCEPT, a multi-arm Phase 1/2 precision-based platform trial at MD Anderson Cancer Center evaluating novel …
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Multiple CAR-T Cell Therapy Targeting AML [Phase 1, Phase 2]
A clinical trial update reporting Phase 1 and Phase 2 studies of multiple CAR-T cell therapies targeting acute myeloid leukemia, currently r…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Multi-CAR T Cell Therapy for Acute Myeloid Leukemia [Phase 1, Phase 2]
A multi-CAR T cell therapy is being studied in Phase 1/Phase 2 for acute myeloid leukemia; recruitment is ongoing.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial) [Phase 2]
This is a Phase 2 screening trial (MYELOMATCH) sponsored by the National Cancer Institute to assign people with myeloid cancers to a treatme…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial) [Phase 2]
Phase 2 clinical trial update for a study evaluating novel therapeutics in newly diagnosed high-risk acute myeloid leukemia; the trial is cu…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial) [Phase 2]
Phase 2 trial in younger patients with intermediate-risk acute myeloid leukemia compares cytarabine + daunorubicin with and without venetocl…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Universal 4SCAR7U Targeting CD7-positive Malignancies [Phase 1]
A Phase 1 trial evaluating Universal 4SCAR7U, a CD7-targeting therapy from Shenzhen Geno-Immune Medical Institute, is currently recruiting. …
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Phase I Study Of PLM-102 In Patients With Relapsed And Refractory Acute Myeloid Leukemia [Phase 1]
This document reports a Phase I clinical trial evaluating PLM-102 in adults with relapsed or refractory acute myeloid leukemia, which is cur…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Monitoring, Detoxifying, and Rebalancing Metals During Acute Myeloid Leukemia (AML) Therapy, a Phase 2 Randomized Study [Phase 2]
Describes a Phase 2 randomized clinical trial at MD Anderson Cancer Center evaluating monitoring, detoxification, and rebalancing of metals …
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study of BGB-11417 in Participants With Myeloid Malignancies [Phase 1, Phase 2]
BeiGene is testing BGB-11417 in Phase 1/2 trials for myeloid malignancies, including acute myeloid leukemia and myelodysplastic syndromes, w…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: 8-Chloroadenosine in Combination With Venetoclax for the Treatment of Patients With Relapsed/Refractory Acute Myeloid Leukemia [Phase 1]
A Phase 1 trial of 8-Chloroadenosine in combination with venetoclax for relapsed/refractory acute myeloid leukemia is currently suspended.
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Study on the Efficacy and Safety of the TmBU Conditioning Regimen in High-risk or Relapsed/Refractory Acute Leukemia [Phase 2]
A Phase 2 clinical trial evaluating the efficacy and safety of the TmBU Conditioning Regimen in high-risk or relapsed/refractory acute leuke…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Pilot Imaging Study of Leukemia [Phase 1]
Phase 1 pilot imaging study in leukemia is currently recruiting. Conditions listed include acute lymphoblastic leukemia, acute myeloid leuke…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Functionally Optimized CD33 CAR-T Cell Therapy Targeting Recurrent/Refractory Acute Myeloid Leukemia [Phase 1]
A Phase 1 clinical trial update describes a functionally optimized CD33 CAR-T cell therapy targeting recurrent/refractory acute myeloid leuk…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Randomized Study to Compare Post-transplant Cyclophosphamide, Sirolimus, Ruxolitinib and Post-transplant Cyclophosphamide, Sirolimus, Mycophenolate Mofetil to Prevent Graft Versus Host Disease [Phase 2]
A Phase 2 randomized trial at MD Anderson Cancer Center compares two GVHD prophylaxis regimens after allogeneic stem cell transplantation in…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Ruxolitinib With Azacitidine Maintenance for the Treatment of Patients With Acute Myeloid Leukemia Undergoing Reduced Intensity Allogeneic Stem Cell Transplantation [Phase 1]
Phase 1 clinical trial evaluating ruxolitinib with azacitidine maintenance for Acute Myeloid Leukemia patients undergoing reduced-intensity …
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Imetelstat Combinations in Relapsed AML [Phase 1]
Clinical trial update notes a Phase 1 study of imetelstat in combination regimens for relapsed acute myeloid leukemia, currently recruiting.