Acute Myeloid Leukemia with Myelodysplasia-related Changes
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial) [Phase 2]
This is a Phase 2 screening trial (MYELOMATCH) sponsored by the National Cancer Institute to assign people with myeloid cancers to a treatme…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: CPX-351 and Glasdegib for Newly Diagnosed Acute Myelogenous Leukemia With MDS Related Changes or Therapy-related Acute Myeloid Leukemia [Phase 2]
Phase 2 trial update evaluating CPX-351 in combination with glasdegib for newly diagnosed acute myeloid leukemia with myelodysplasia-related…
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CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: Guadecitabine and Atezolizumab in Treating Patients With Advanced Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia That Is Refractory or Relapsed [Phase 1, Phase 2]
Phase 1/2 study of guadecitabine plus atezolizumab in adults with advanced myelodysplastic syndrome or chronic myelomonocytic leukemia that …
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: CPX-351 for the Treatment of Secondary Acute Myeloid Leukemia in Patients Younger Than 60 Years Old [Phase 2]
Phase 2 trial update of CPX-351 for secondary acute myeloid leukemia in patients under 60; the study is currently active but not recruiting,…
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Comparing the Addition of an Anti-Cancer Drug, Pomalidomide, to the Usual Chemotherapy Treatment (Daunorubicin and Cytarabine Liposome) in Newly Diagnosed Acute Myeloid Leukemia With Myelodysplastic Syndrome-Related Changes [Phase 2]
Phase 2 trial evaluating adding pomalidomide to the standard liposomal daunorubicin/cytarabine chemotherapy in newly diagnosed acute myeloid…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Pevonedistat, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating pevonedistat with cytarabine and idarubicin for various forms of acute myeloid leukemia, including thera…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: VYxeoS Liposomal Italian Observational Study iN the Real Practice
A real-world observational study in Italy evaluating Vyxeos (CPX-351) for acute myeloid leukemia and its subtypes has completed.
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CLINICAL_TRIALS trial_result · 2025-05-21Clinical Trial Update: Daratumumab and Donor Lymphocyte Infusion in Treating Participants With Relapsed Acute Myeloid Leukemia After Stem Cell Transplant [Phase 1, Phase 2]
A Phase 1/2 trial evaluating daratumumab plus donor lymphocyte infusion in relapsed acute myeloid leukemia after stem cell transplantation w…
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Compare the Efficacy and Safety of Dec-FB4 and FB4 as Conditioning Regimen for AML-MR [Phase 3]
A Phase 3 clinical trial is planned to compare Dec-FB4 and FB4 as conditioning regimens for acute myeloid leukemia with myelodysplasia-relat…
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CLINICAL_TRIALS trial_result · 2023-06-09Clinical Trial Update: High Dose Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil in Preventing Graft Versus Host Disease in Patients With Hematological Malignancies Undergoing Myeloablative or Reduced Intensity Donor Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating high-dose cyclophosphamide, tacrolimus, and mycophenolate mofetil to prevent graft-versus-host disease in …
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FDA approval · 2022-09-27FDA Approved: VYXEOS — Supplemental Application (Jazz Pharmaceuticals, Inc.)
The FDA approved a supplemental application for VYXEOS (daunorubicin and cytarabine liposome) from Jazz Pharmaceuticals, Inc. This action re…
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FDA approval · 2017-08-03FDA Approved: VYXEOS — Original Application (Jazz Pharmaceuticals, Inc.)
FDA granted original approval for VYXEOS (daunorubicin and cytarabine liposome) for adults with therapy-related acute myeloid leukemia or ac…
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CLINICAL_TRIALS trial_result · 2014-02-20Clinical Trial Update: Decitabine as Maintenance Therapy After Standard Therapy in Treating Patients With Previously Untreated Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating decitabine as maintenance therapy after standard treatment in adults with previously untreated acute myeloid leukem…