Acute Myeloid Leukemia with 11q23 Abnormalities
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Sirolimus and Azacitidine in Treating Patients With High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia That is Recurrent or Not Eligible for Intensive Chemotherapy [Phase 2]
Phase 2 trial evaluating the combination of sirolimus and azacitidine in adults with high-risk myelodysplastic syndrome or acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: Sirolimus, Idarubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia [EARLY_Phase 1]
A Phase 1 trial evaluating a combination of sirolimus, idarubicin, and cytarabine in adults with newly diagnosed acute myeloid leukemia has …
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CLINICAL_TRIALS trial_result · 2024-05-30Clinical Trial Update: Daunorubicin Hydrochloride, Cytarabine and Oblimersen Sodium in Treating Patients With Previously Untreated Acute Myeloid Leukemia [Phase 3]
Phase 3 trial evaluating daunorubicin hydrochloride, cytarabine, and oblimersen sodium in previously untreated acute myeloid leukemia has co…
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CLINICAL_TRIALS trial_result · 2019-03-05Clinical Trial Update: Infusion of Off-the-Shelf Expanded Cord Blood Cells to Augment Cord Blood Transplant in Patients With Hematologic Malignancies [Phase 2]
Phase 2 clinical trial updating the use of off-the-shelf expanded cord blood cells to augment cord blood transplant in patients with various…
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CLINICAL_TRIALS trial_result · 2018-03-09Clinical Trial Update: Vaccine Therapy and Basiliximab in Treating Patients With Acute Myeloid Leukemia in Complete Remission [Phase 1]
Phase 1 trial update evaluating a cancer vaccine therapy in combination with Basiliximab for adults with acute myeloid leukemia (in remissio…
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CLINICAL_TRIALS trial_result · 2017-09-08Clinical Trial Update: Clofarabine, Cytarabine, and G-CSF in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the combination of clofarabine, cytarabine, and G-CSF in relapsed or refractory acute myeloid leukemia…
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CLINICAL_TRIALS trial_result · 2017-05-15Clinical Trial Update: Clofarabine and Cytarabine in Treating Patients With Acute Myeloid Leukemia With Minimal Residual Disease [Phase 2]
Phase 2 study of the combination of clofarabine and cytarabine in adults with acute myeloid leukemia across various cytogenetic subtypes and…
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Decitabine Followed by Idarubicin and Cytarabine in Treating Patients With Relapsed or Refractory AML and MDS [Phase 2]
Phase 2 clinical trial evaluated a sequence of decitabine followed by idarubicin and cytarabine in adults with relapsed or refractory acute …
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CLINICAL_TRIALS trial_result · 2017-03-10Clinical Trial Update: Ixazomib (MLN9708) in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial update of ixazomib in relapsed or refractory acute myeloid leukemia has been terminated; results were posted previous…
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CLINICAL_TRIALS trial_result · 2016-07-06Clinical Trial Update: Phase I Combination of Midostaurin, Bortezomib, and Chemo in Relapsed/Refractory Acute Myeloid Leukemia [Phase 1]
A Phase I trial evaluating a combination of midostaurin and bortezomib with chemotherapy in relapsed/refractory acute myeloid leukemia has c…
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CLINICAL_TRIALS trial_result · 2015-12-04Clinical Trial Update: Romidepsin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
This Phase 2 trial updates romidepsin for relapsed or refractory acute myeloid leukemia, covering several AML subtypes defined by cytogeneti…
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CLINICAL_TRIALS trial_result · 2015-12-04Clinical Trial Update: Oblimersen, Cytarabine, and Daunorubicin in Treating Older Patients With Acute Myeloid Leukemia [Phase 1]
This Phase 1 clinical trial update reports on the combination of oblimersen (Genasense) with cytarabine and daunorubicin in older adults wit…
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CLINICAL_TRIALS trial_result · 2015-01-07Clinical Trial Update: AKT Inhibitor MK-2206 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating AKT inhibitor MK-2206 in relapsed or refractory adult acute leukemias completed; results posted in 2015.
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CLINICAL_TRIALS trial_result · 2013-11-27Clinical Trial Update: Deferasirox in Treating Iron Overload Caused By Blood Transfusions in Patients With Hematologic Malignancies [Phase 2]
Phase 2 trial updating the use of deferasirox for iron overload due to transfusions in patients with hematologic malignancies; study status …
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CLINICAL_TRIALS trial_result · 2013-10-28Clinical Trial Update: Low-Dose or High-Dose Conditioning Followed by Peripheral Blood Stem Cell Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Myelogenous Leukemia [Phase 3]
Phase 3 trial evaluating low-dose or high-dose conditioning regimens before peripheral blood stem cell transplantation in patients with myel…
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CLINICAL_TRIALS trial_result · 2013-06-04Clinical Trial Update: Combination Chemotherapy With or Without Valspodar in Treating Patients With Previously Untreated Acute Myeloid Leukemia [Phase 3]
Phase 3 trial evaluating whether adding the P-glycoprotein modulator valspodar to standard chemotherapy improves outcomes in adults with pre…
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CLINICAL_TRIALS trial_result · 2013-06-04Clinical Trial Update: GTI-2040 and High-Dose Cytarabine in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia [Phase 1]
A Phase 1 clinical trial evaluating GTI-2040 in combination with high-dose cytarabine in adults with refractory or relapsed acute myeloid le…
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CLINICAL_TRIALS trial_result · 2013-02-05Clinical Trial Update: Bortezomib, Daunorubicin, and Cytarabine in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia [Phase 1, Phase 2]
This update reports on a Phase 1/2 clinical trial evaluating the combination of bortezomib, daunorubicin, and cytarabine in older patients w…
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CLINICAL_TRIALS trial_result · 2013-01-24Clinical Trial Update: Idarubicin and Cytarabine With or Without Bevacizumab in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 2]
Phase 2 trial of idarubicin and cytarabine with or without bevacizumab for newly diagnosed acute myeloid leukemia was terminated.
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CLINICAL_TRIALS trial_result · 2013-01-07Clinical Trial Update: Vorinostat and Decitabine in Treating Patients With Relapsed, Refractory, or Poor-Prognosis Hematologic Cancer or Other Diseases [Phase 1]
This Phase 1 trial evaluates the safety and feasibility of combining vorinostat with decitabine in adults with relapsed, refractory, or poor…