Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Vorinostat and Azacitidine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid Leukemia [Phase 1, Phase 2]
This clinical trial update reports a Phase 1/2 study of the combination of vorinostat and azacitidine in patients with myelodysplastic syndr…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Addition of an Anti-cancer Drug, Navtemadlin, to the Usual Treatments (Cytarabine and Idarubicin) in Patients With Acute Myeloid Leukemia [Phase 1]
Phase 1 clinical trial update evaluating the addition of navtemadlin to standard cytarabine and idarubicin in patients with acute myeloid le…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: Liposome-encapsulated Daunorubicin-Cytarabine and Gemtuzumab Ozogamicin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome [Phase 2]
Phase 2 trial evaluating liposome-encapsulated daunorubicin-cytarabine (CPX-351) in combination with gemtuzumab ozogamicin for relapsed or r…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Hu8F4 in Treating Patients With Advanced Hematologic Malignancies [Phase 1]
Hu8F4 is being studied in a Phase 1 trial for multiple advanced hematologic malignancies; the study is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: CPX-351 for the Treatment of Secondary Acute Myeloid Leukemia in Patients Younger Than 60 Years Old [Phase 2]
Phase 2 trial update of CPX-351 for secondary acute myeloid leukemia in patients under 60; the study is currently active but not recruiting,…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Cognitive Behavioral Therapy in Helping Patients With Acute Myeloid Leukemia or Lymphoma With Cancer-Related Fatigue [Phase 2]
This Phase 2 trial evaluates cognitive behavioral therapy to reduce cancer-related fatigue in patients with acute myeloid leukemia and lymph…
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: BLAST MRD AML-2: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 2- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Azacitidine and Venetoclax as Frontline Therapy in Unfit Patients With Acute Myeloid Leukemia [Phase 2]
Phase 2 randomized trial evaluating pembrolizumab added to azacitidine and venetoclax as frontline therapy for unfit acute myeloid leukemia …
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CLINICAL_TRIALS trial_result · 2024-04-02Clinical Trial Update: Topotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Disorders and Acute Myeloid Leukemia or Chronic Myelomonocytic Leukemia [Phase 2]
Phase 2 trial update evaluating topotecan hydrochloride and carboplatin with or without veliparib for advanced myeloproliferative disorders …
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CLINICAL_TRIALS trial_result · 2023-11-07Clinical Trial Update: Donor Natural Killer Cells and Donor Stem Cell Transplant in Treating Patients With High Risk Myeloid Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating donor natural killer cells and donor stem cell transplant in high-risk myeloid malignancies; completed w…
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CLINICAL_TRIALS trial_result · 2023-02-09Clinical Trial Update: Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation and Donor Bone Marrow Transplant in Treating Patients With Advanced Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or High-Risk Myelodysplastic Syndrome [Phase 1]
Phase 1 trial of a conditioning regimen including an iodine-131 labeled monoclonal antibody with fludarabine, cyclophosphamide, total-body i…
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CLINICAL_TRIALS trial_result · 2021-10-04Clinical Trial Update: Targeted Therapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myelogenous Leukemia [Phase 2]
Phase 2 trial update on a targeted therapy for relapsed/refractory acute lymphoblastic leukemia and acute myeloid leukemia; trial status ter…
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CLINICAL_TRIALS trial_result · 2020-05-14Clinical Trial Update: Lenalidomide in Treating Older Patients With Acute Myeloid Leukemia Who Have Undergone Stem Cell Transplant [Phase 1, Phase 2]
Clinical trial investigating lenalidomide in older AML patients post-stem cell transplant; study terminated with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-01-07Clinical Trial Update: Erlotinib Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial evaluating erlotinib hydrochloride in relapsed or refractory acute myeloid leukemia has completed with posted results…
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CLINICAL_TRIALS trial_result · 2019-09-24Clinical Trial Update: Lirilumab and Azacitidine in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating lirilumab with azacitidine in refractory or relapsed acute myeloid leukemia was terminated; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2016-10-24Clinical Trial Update: Decitabine With or Without Bortezomib in Treating Older Patients With Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating decitabine with or without bortezomib in older adults with acute myeloid leukemia; study completed with results pos…
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CLINICAL_TRIALS trial_result · 2015-08-20Clinical Trial Update: Azacitidine, Mitoxantrone Hydrochloride, and Etoposide in Treating Older Patients With Poor-Prognosis Acute Myeloid Leukemia [Phase 1]
A Phase 1 study evaluating a combination of azacitidine, mitoxantrone hydrochloride, and etoposide in older patients with poor-prognosis acu…
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CLINICAL_TRIALS trial_result · 2014-12-23Clinical Trial Update: Lenalidomide, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia [Phase 1]
Phase 1 clinical trial evaluating a combination of lenalidomide, cytarabine, and idarubicin in adults with acute myeloid leukemia; the study…
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CLINICAL_TRIALS trial_result · 2014-08-12Clinical Trial Update: Combination Chemotherapy and Dasatinib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial assessing combination chemotherapy with dasatinib for newly diagnosed acute myeloid leukemia; completed with results …