Megakaryoblastic Leukemia

CLINICAL_TRIALS trial_result · 2026-04-13

Clinical Trial Update: Vorinostat and Azacitidine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid Leukemia [Phase 1, Phase 2]

This clinical trial update reports a Phase 1/2 study of the combination of vorinostat and azacitidine in patients with myelodysplastic syndr…

CLINICAL_TRIALS trial_result · 2025-04-29

Clinical Trial Update: Sirolimus, Idarubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia [EARLY_Phase 1]

A Phase 1 trial evaluating a combination of sirolimus, idarubicin, and cytarabine in adults with newly diagnosed acute myeloid leukemia has …

CLINICAL_TRIALS trial_result · 2025-01-01

Clinical Trial Update: Cord Blood Transplant With Dilanubicel for the Treatment of HIV Positive Hematologic Cancers [Phase 2]

Phase 2 trial evaluating cord blood transplant with Dilanubicel for HIV-positive hematologic cancers; the study was terminated and results w…

CLINICAL_TRIALS trial_result · 2023-11-07

Clinical Trial Update: Donor Natural Killer Cells and Donor Stem Cell Transplant in Treating Patients With High Risk Myeloid Malignancies [Phase 1, Phase 2]

Phase 1/2 clinical trial evaluating donor natural killer cells and donor stem cell transplant in high-risk myeloid malignancies; completed w…

CLINICAL_TRIALS trial_result · 2020-12-19

Clinical Trial Update: Alisertib in Treating Patients With Myelofibrosis or Relapsed or Refractory Acute Megakaryoblastic Leukemia [NA]

Clinical trial update on alisertib in patients with myelofibrosis or relapsed/refractory acute megakaryoblastic leukemia (AMKL).

CLINICAL_TRIALS trial_result · 2018-07-26

Clinical Trial Update: AML Therapy With Irradiated Allogeneic Cells [NA]

Clinical trial update for irradiated allogeneic cell therapy in various adult acute myeloid leukemia subtypes; the study is terminated with …

CLINICAL_TRIALS trial_result · 2017-04-17

Clinical Trial Update: Treatment for Relapsed/Refractory AML Based on a High Throughput Drug Sensitivity Assay [NA]

Clinical trial update on using a high-throughput drug sensitivity assay to guide treatment for relapsed/refractory acute myeloid leukemia.

CLINICAL_TRIALS withdrawal · 2017-04-05

Clinical Trial Update: A Study of Volasertib Plus Induction Chemotherapy for Acute Myeloid Leukemia [Phase 1]

Phase 1 study of volasertib plus induction chemotherapy for acute myeloid leukemia has been withdrawn.

CLINICAL_TRIALS trial_result · 2017-03-31

Clinical Trial Update: Decitabine Followed by Idarubicin and Cytarabine in Treating Patients With Relapsed or Refractory AML and MDS [Phase 2]

Phase 2 clinical trial evaluated a sequence of decitabine followed by idarubicin and cytarabine in adults with relapsed or refractory acute …

CLINICAL_TRIALS trial_result · 2017-03-10

Clinical Trial Update: Ixazomib (MLN9708) in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]

Phase 2 clinical trial update of ixazomib in relapsed or refractory acute myeloid leukemia has been terminated; results were posted previous…

CLINICAL_TRIALS research · 2016-05-19

Clinical Trial Update: Biomarkers in Bone Marrow Samples From Pediatric Patients With High-Risk Acute Myeloid Leukemia

A completed pediatric AML biomarker study update from the Children's Oncology Group examining biomarkers in bone marrow from high-risk AML p…

CLINICAL_TRIALS trial_result · 2016-05-18

Clinical Trial Update: Studying Genes in Samples From Younger Patients With Acute Megakaryoblastic Leukemia

A study investigating genetic factors in samples from children with acute megakaryoblastic leukemia (AMKL) and related pediatric AML has com…

CLINICAL_TRIALS trial_result · 2016-05-09

Clinical Trial Update: Omacetaxine Mepesuccinate, Cytarabine, and Decitabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 2]

Phase 2 trial evaluating a three-drug regimen of omacetaxine mepesuccinate, cytarabine, and decitabine in older adults with newly diagnosed …

CLINICAL_TRIALS trial_result · 2016-02-23

Clinical Trial Update: Biomarkers in Samples From Patients With Down Syndrome and Acute Megakaryoblastic Leukemia

Clinical trial update summarizing biomarker analyses from samples of patients with Down syndrome-associated acute megakaryoblastic leukemia …

CLINICAL_TRIALS trial_result · 2015-06-19

Clinical Trial Update: Cholecalciferol in Treating Patients With Acute Myeloid Leukemia Undergoing Intensive Induction Chemotherapy [Phase 2]

Phase 2 trial evaluating cholecalciferol (Vitamin D3) in adults with acute myeloid leukemia undergoing intensive induction chemotherapy; the…

CLINICAL_TRIALS trial_result · 2015-01-07

Clinical Trial Update: AKT Inhibitor MK-2206 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]

Phase 2 trial evaluating AKT inhibitor MK-2206 in relapsed or refractory adult acute leukemias completed; results posted in 2015.

CLINICAL_TRIALS trial_result · 2013-02-05

Clinical Trial Update: Bortezomib, Daunorubicin, and Cytarabine in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia [Phase 1, Phase 2]

This update reports on a Phase 1/2 clinical trial evaluating the combination of bortezomib, daunorubicin, and cytarabine in older patients w…

CLINICAL_TRIALS trial_result · 2013-01-24

Clinical Trial Update: Idarubicin and Cytarabine With or Without Bevacizumab in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 2]

Phase 2 trial of idarubicin and cytarabine with or without bevacizumab for newly diagnosed acute myeloid leukemia was terminated.

CLINICAL_TRIALS trial_result · 2013-01-11

Clinical Trial Update: SB-715992 in Treating Patients With Acute Leukemia, Chronic Myelogenous Leukemia, or Advanced Myelodysplastic Syndromes [Phase 1]

This Phase 1 trial evaluated SB-715992 in adults with various acute leukemias, chronic myeloid leukemia in blast phase, and advanced myelody…

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