Leukemia of Ambiguous Lineage
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia [Phase 2]
Phase 2 study recruiting to test adding venetoclax and/or blinatumomab to standard chemotherapy in infants with newly diagnosed KMT2A-rearra…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia [Phase 2]
This clinical trial update describes a Phase 2 study of revumenib in combination with chemotherapy for relapsed or refractory leukemia, with…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation [Phase 1, Phase 2]
A phase 1/2 trial evaluating Revumenib in relapsed/refractory leukemias including MLL/KMT2A rearrangements or NPM1 mutations; currently recr…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Randomization for the Identification of Best Treatment Intensity for Less Fit Adults With Acute Myeloid Leukemia and Myeloid Neoplasms [NA]
This clinical trial update describes a randomization study to identify the best treatment intensity for less fit adults with acute myeloid l…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Venetoclax Basket Trial for High Risk Hematologic Malignancies [Phase 1]
A Phase 1 Venetoclax basket trial across multiple high-risk hematologic malignancies is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Revumenib for the Treatment of Acute Leukemia in Patients Post-Allogeneic Stem Cell Transplant [Phase 1]
A Phase 1 clinical trial evaluating Revumenib for acute leukemia in patients after allogeneic stem cell transplant; the study is currently r…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia [Phase 1]
This Phase 1 trial tests a triple-drug regimen of Revumenib, azacitidine, and venetoclax in pediatric and young adult patients with refracto…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Combination Chemotherapy (FLAG-Ida) Followed Immediately by Reduced-Intensity Total Body Radiation Therapy and Donor Hematopoietic Cell Transplant for the Treatment of Adults Age 60 and Older With Newly Diagnosed Adverse-Risk Acute Myeloid Leukemia or Other High-Grade Myeloid Cancer [Phase 2]
Phase 2 clinical trial evaluating FLAG-Ida chemotherapy followed by reduced-intensity total body irradiation and donor hematopoietic cell tr…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia [Phase 1]
Phase 1 clinical trial update evaluating the combination of selinexor and venetoclax with chemotherapy in pediatric and young adult patients…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases [Phase 2]
Phase 2 clinical trial evaluating a cord blood transplant using cyclophosphamide, fludarabine, and total-body irradiation in high-risk hemat…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Venetoclax Combined With Azactidine in the Treatment of ALAL [Phase 2]
A Phase 2 clinical trial assessing venetoclax combined with azacitidine for acute leukemia of ambiguous lineage is currently recruiting.
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CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating naive T cell depletion to prevent chronic graft-versus-host disease in children and young adults receiving…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Efficacy of Acute Lymphoblastic Leukemia-Based Therapy in Treating Patients With Acute Leukemia of Ambiguous Lineage [Phase 2]
This clinical trial update indicates a Phase 2 study evaluating an acute lymphoblastic leukemia-based therapy for acute leukemia of ambiguou…
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CLINICAL_TRIALS withdrawal · 2025-06-22Clinical Trial Update: A Study of JNJ-75276617 in Combination With Conventional Chemotherapy for Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias [Phase 1]
A Phase 1 trial of JNJ-75276617 in combination with conventional chemotherapy for pediatric and young adult patients with relapsed/refractor…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD [Phase 2]
Phase 2 clinical trial assessing selective depletion of CD45RA+ T cells from allogeneic stem cell grafts to prevent graft-versus-host diseas…
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CLINICAL_TRIALS research · 2025-04-17Clinical Trial Update: Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST) Trial [Phase 2]
Phase 2 trial evaluating fecal microbiota transplantation before allogeneic stem cell transplant; recruitment is ongoing across multiple hem…
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CLINICAL_TRIALS trial_result · 2024-03-19Clinical Trial Update: Clofarabine, Idarubicin, Cytarabine, Vincristine Sulfate, and Dexamethasone in Treating Patients With Newly Diagnosed or Relapsed Mixed Phenotype Acute Leukemia [Phase 2]
Phase 2 trial evaluating a multi-drug regimen (clofarabine, idarubicin, cytarabine, vincristine, and dexamethasone) in newly diagnosed or re…
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CLINICAL_TRIALS trial_result · 2021-11-01Clinical Trial Update: Higher or Lower Dose Cladribine, Cytarabine, and Mitoxantrone in Treating Medically Less Fit Patients With Newly Diagnosed Acute Myeloid Leukemia or Myeloid Neoplasm [Phase 2]
Phase 2 trial evaluating higher or lower doses of cladribine, cytarabine, and mitoxantrone in medically less fit patients with newly diagnos…
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CLINICAL_TRIALS trial_result · 2021-10-26Clinical Trial Update: Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement [Phase 2]
Phase 2 trial evaluating azacitidine with combination chemotherapy in infants with KMT2A-rearranged acute lymphoblastic leukemia and related…
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CLINICAL_TRIALS trial_result · 2021-06-30Clinical Trial Update: High Throughput Drug Sensitivity Assay and Genomics- Guided Treatment of Patients With Relapsed or Refractory Acute Leukemia [NA]
Clinical trial update on high-throughput drug sensitivity assay and genomics-guided treatment for relapsed or refractory acute leukemia; stu…