Decompensated Heart Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-08-25Clinical Trial Update: Usefulness of Lung Ultrasound in Ambulatory Management of Patients With Chronic Heart Failure [Phase 3]
A Phase 3 trial evaluating the usefulness of lung ultrasound in ambulatory management of patients with chronic heart failure has been termin…
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CLINICAL_TRIALS trial_result · 2017-07-25Clinical Trial Update: Impact of Therapy Optimization on the Level of Biomarkers in Patients With Decompensated Heart Failure
A completed clinical trial evaluating how optimizing heart failure therapy influences biomarker levels in patients with decompensated heart …
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CLINICAL_TRIALS research · 2017-05-19Clinical Trial Update: Manipal Heart Failure Registry (MHFR)
Clinical trial update on the Manipal Heart Failure Registry, documenting ongoing observational research on heart failure conditions.
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CLINICAL_TRIALS trial_result · 2017-04-11Clinical Trial Update: Model for Heart Failure ExAcerbation Reduction Trial
The Cleveland Clinic Florida completed a clinical trial evaluating a model designed to reduce heart failure exacerbations in patients with a…
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CLINICAL_TRIALS trial_result · 2017-04-10Clinical Trial Update: REWORD-HF REverse WOrsening Renal Function in Decompensated Heart Failure [Phase 4]
A Phase 4 clinical trial evaluating whether REWORD-HF can reverse renal function worsening in acute decompensated heart failure was terminat…
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CLINICAL_TRIALS withdrawal · 2017-03-24Clinical Trial Update: A Study to Investigate the Safety and Efficacy of a Novel Furosemide Regimen [Phase 1, Phase 2]
A study evaluating a novel furosemide regimen for acute decompensated heart failure has been withdrawn from Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2017-03-20Clinical Trial Update: Efficacy and Safety of Treatment With Simdax® Versus Dobutrex® in Decompensated Heart Failure Patients. [Phase 4]
This Phase 4 trial compares the efficacy and safety of Simdax (levosimendan) versus Dobutrex (dobutamine) in patients with decompensated hea…
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CLINICAL_TRIALS research · 2017-01-04Clinical Trial Update: Speckle Tracking Echocardiography Adds Information in Decompensated Heart Failure
This clinical trial update notes that speckle tracking echocardiography provides additional information in patients with acute decompensated…
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CLINICAL_TRIALS research · 2017-01-02Clinical Trial Update: Control of Sinus Node Tachycardia as an Additional Therapy in Patients With Decompensated Heart Failure [Phase 1, Phase 2]
This clinical trial update discusses a Phase 1/2 study evaluating control of sinus node tachycardia as an additional therapy for patients wi…
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CLINICAL_TRIALS withdrawal · 2016-09-07Clinical Trial Update: A Prospective, Single-center, Randomized, Controlled, Open-label, Pilot Study to Compare the Effectiveness and Safety of DIuretics Add-On Strategy in Acute Decompensated Heart Failure Patients (DIOS II) [NA]
The DIOS II trial, a prospective pilot study evaluating diuretic add-on strategies in acute decompensated heart failure, has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-01-28Clinical Trial Update: Tolvaptan/Ultrafiltration in the Treatment of Acute Heart Failure [Phase 4]
A Phase 4 clinical trial evaluating tolvaptan with ultrafiltration for acute decompensated heart failure has completed.
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CLINICAL_TRIALS trial_result · 2015-11-18Clinical Trial Update: Study to Evaluate the Effectiveness of Cardiac Rehabilitation (Rehab) for Acute Decompensated Heart Failure Patients on 6 Minute Walk Test and Quality of Life [NA]
A clinical trial evaluating a cardiac rehabilitation program for heart failure patients was terminated. The study assessed outcomes using th…
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CLINICAL_TRIALS trial_result · 2015-10-12Clinical Trial Update: Study of Heart Failure Hospitalizations After Aquapheresis Therapy Compared to Intravenous (IV) Diuretic Treatment [NA]
Clinical trial update for aquapheresis versus IV diuretics in heart failure; study terminated with results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-10-08Clinical Trial Update: A Phase IIb Study to Investigate the Efficacy and Tolerability of Cinaciguat (150 µg/h, 100 µg/h, 50 µg/h) Given Intravenously to Subjects With Acute Decompensated Chronic Congestive Heart Failure (ADHF) [Phase 2]
A Phase IIb study evaluating intravenous Cinaciguat in patients with acute decompensated heart failure was terminated.
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CLINICAL_TRIALS trial_result · 2015-10-08Clinical Trial Update: A Phase IIb Study to Investigate the Efficacy and Tolerability of Lower Doses Cinaciguat (25 µg/h, 10 µg/h) Given Intravenously to Patients With Acute Decompensated Chronic Congestive Heart Failure (ADHF) [Phase 2]
This update reports the termination of a Phase IIb trial evaluating low-dose intravenous cinaciguat in patients with acute decompensated hea…
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CLINICAL_TRIALS research · 2015-09-28Clinical Trial Update: Role of the Mespere Venus 1000 in Predicting Heart Failure Hospital Readmissions
Clinical trial update on using the Mespere Venus 1000 device to predict hospital readmissions in patients with acute decompensated heart fai…
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CLINICAL_TRIALS research · 2015-09-23Clinical Trial Update: Acute Congestive Heart Failure [NA]
Clinical trial update related to acute decompensated heart failure and acute cardiogenic pulmonary edema, sponsored by RWTH Aachen Universit…
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CLINICAL_TRIALS trial_result · 2015-06-25Clinical Trial Update: Role of Natriuretic Peptides in the Treatment of Acutely Decompensated Heart Failure Patient With Obstructive Airways Disease [Phase 3]
A Phase 3 trial evaluating natriuretic peptides for acutely decompensated heart failure in patients with obstructive airway disease has been…
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: Assessment of Coronary Flow Reserve in Heart Failure Patients After Ultrafiltration Versus Diuretics [NA]
The study compared ultrafiltration to diuretics in patients with acute decompensated heart failure to assess coronary flow reserve; the tria…
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CLINICAL_TRIALS research · 2015-06-04Clinical Trial Update: Evaluation of Circulating Levels of Adult Stem Cells in the Peripheral Blood of Patients With Acute Decompensated Heart Failure and Following Stabilization, in Comparison With Healthy Volunteers
A completed clinical trial evaluating circulating levels of adult stem cells in the peripheral blood of patients with acute decompensated he…
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CLINICAL_TRIALS trial_result · 2015-01-22Clinical Trial Update: Utility of Neutrophil Gelatinase-associated Lipocalin (NGAL) in Predicting Renal Impairment, Further Decompensation and Rehospitalization in Acutely Decompensated and Chronic Heart Failure Patients
A completed clinical trial evaluating whether the biomarker NGAL can predict renal impairment, further decompensation, and rehospitalization…
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CLINICAL_TRIALS research · 2014-12-24Clinical Trial Update: Pilot Study for the Evaluation of the Safety and Performance of the RenaSense System in Hospitalized Acute Decompensated Heart Failure Patients [Phase 1, Phase 2]
Pilot study to evaluate the safety and performance of the RenaSense System in hospitalized patients with acute decompensated heart failure, …
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CLINICAL_TRIALS trial_result · 2014-12-03Clinical Trial Update: Serial Measurements of Biomarker in Patients With Acute Decompensated Heart Failure
The document reports on a completed clinical trial that involved serial biomarker measurements in patients with acute decompensated heart fa…
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CLINICAL_TRIALS withdrawal · 2014-10-23Clinical Trial Update: Safety and Efficacy Study of Istaroxime in Acute Decompensated Heart Failure Patients [Phase 2]
A Phase 2 trial evaluating istaroxime for acute decompensated heart failure was withdrawn from the study.
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FDA approval · 2014-09-03FDA Approved: MILRINONE LACTATE — Original Application (Hospira, Inc.)
FDA approved Hospira's milrinone lactate injection as an original ANDA, granting a generic version of milrinone lactate.