Chest Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Ultrasound Acute Chest Syndrome Sickle Cell Disease [NA]
A clinical trial update shows an ultrasound study evaluating treatment for Acute Chest Syndrome in Sickle Cell Disease is currently recruiti…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Tocilizumab for Acute Chest Syndrome [Phase 2]
This is a Phase 2 clinical trial evaluating Tocilizumab for Acute Chest Syndrome in patients with sickle cell disease; recruitment is ongoin…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Morphine Clearance and Glomerular Filtration in Sickle Cell Patients in Crisis in Intensive Care [NA]
A clinical trial update announcing recruitment for a study on morphine clearance and glomerular filtration in sickle cell crisis patients in…
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: Daily Vitamin D for Sickle-cell Respiratory Complications [Phase 2]
Phase 2 trial evaluating daily vitamin D for sickle cell–related respiratory complications has completed and posted results.
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Awake Prone Positioning for Severe Acute Chest Syndrome [NA]
Trial NCT06698120 is evaluating awake prone positioning for severe Acute Chest Syndrome in sickle cell disease. The study is not yet recruit…
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CLINICAL_TRIALS trial_result · 2025-06-25Clinical Trial Update: Use of Macrolides in Acute Chest Syndrome: A Multicenter Retrospective Study
A multicenter retrospective study evaluates the use of macrolide antibiotics in acute chest syndrome among patients with sickle cell disease…
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: Combined Use of a Respiratory Broad Panel Multiplex PCR and Procalcitonin to Reduce Antibiotics Exposure in Hospitalized Sickle-cell Adults With Acute Chest Syndrome. [NA]
Completed clinical trial evaluating the combined use of a respiratory broad panel multiplex PCR and procalcitonin to reduce antibiotic expos…
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CLINICAL_TRIALS trial_result · 2025-03-11Clinical Trial Update: Efficacy and Safety of Tocilizumab for Acute Chest Syndrome Treatment in Patients With Sickle Cell Disease [Phase 3]
This Phase 3 clinical trial is evaluating the efficacy and safety of tocilizumab for treating acute chest syndrome in patients with sickle c…
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: Vitamin D for Sickle-cell Respiratory Complications [Phase 2]
Phase 2 trial evaluating Vitamin D supplementation for respiratory complications in sickle cell disease has completed and results were poste…
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CLINICAL_TRIALS trial_result · 2024-02-09Clinical Trial Update: Therapeutic Anticoagulation Strategy for Acute Chest Syndrome [Phase 3]
A Phase 3 trial evaluating therapeutic anticoagulation strategy for Acute Chest Syndrome in sickle cell disease.
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CLINICAL_TRIALS trial_result · 2023-12-08Clinical Trial Update: Defibrotide in Sickle Cell Disease-Related Acute Chest Syndrome [Phase 2]
Phase 2 trial update on defibrotide for sickle cell disease–related acute chest syndrome has completed.
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CLINICAL_TRIALS trial_result · 2022-05-24Clinical Trial Update: Effect of Platelet Inhibition and / or Lipid Lowering in Non-ACS-patients With Positive Troponin [Phase 3]
Phase 3 clinical trial assessing the effect of platelet inhibition and/or lipid lowering in non-ACS patients with positive troponin was term…
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CLINICAL_TRIALS trial_result · 2019-07-16Clinical Trial Update: Feasibility Study of Unfractionated Heparin in Acute Chest Syndrome [Phase 2]
A Phase 2 feasibility trial of unfractionated heparin for acute chest syndrome in sickle cell disease was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2018-12-11Clinical Trial Update: Bi-Level Positive Airway Ventilation for Acute Chest Syndrome [NA]
Clinical trial update for Bi-Level Positive Airway Ventilation in Acute Chest Syndrome; study terminated with results posted.
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CLINICAL_TRIALS withdrawal · 2018-06-21Clinical Trial Update: A Pilot Study of Azithromycin Prophylaxis for Acute Chest Syndrome in Sickle Cell Disease [Phase 1]
A Phase 1 pilot trial evaluating azithromycin prophylaxis to prevent acute chest syndrome in sickle cell disease has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-02-17Clinical Trial Update: Inhaled Corticosteroid Use to Prevent Acute Chest Syndrome Recurrence in Children Between 1 and 4 With Sickle Cell Disease: a Feasibility Trial [Phase 1]
Phase 1 feasibility trial evaluating inhaled corticosteroids to prevent recurrence of acute chest syndrome in children aged 1-4 with sickle …
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CLINICAL_TRIALS trial_result · 2015-12-15Clinical Trial Update: ST Elevation in Acute Chest Pain; Could Measurement of Lipoprotein-associated Phospholipase A2 (Lp-PLA2) be Helpful to the Clinician?
A completed clinical trial evaluated whether measuring lipoprotein-associated phospholipase A2 (Lp-PLA2) could help clinicians assess ST-seg…
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CLINICAL_TRIALS trial_result · 2015-03-25Clinical Trial Update: Arginine Treatment of Acute Chest Syndrome (Pneumonia) in Sickle Cell Disease Patients [Phase 2]
Phase 2 trial evaluating L-arginine for acute chest syndrome in sickle cell disease patients has completed.
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CLINICAL_TRIALS trial_result · 2014-12-04Clinical Trial Update: Nitric Oxide Therapy for Acute Chest Syndrome in Sickle Cell Disease Children [Phase 2]
Phase 2 trial evaluated inhaled nitric oxide for treating Acute Chest Syndrome in children with Sickle Cell Disease; the study status is com…
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CLINICAL_TRIALS trial_result · 2014-03-04Clinical Trial Update: IMPACTS Trial: Investigation of the Modulation of Phospholipase in Acute Chest Syndrome [Phase 2]
A Phase 2 study (IMPACTS) evaluating varespladib, a phospholipase A2 inhibitor, for acute chest syndrome in sickle cell disease has complete…
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CLINICAL_TRIALS research · 2013-08-02Clinical Trial Update: Effect of Inhaled Nitric Oxide in Acute Chest Syndrome (INOSTA Study) [Phase 2, Phase 3]
Clinical trial update noting the completion of the INOSTA study evaluating inhaled nitric oxide for acute chest syndrome in sickle cell dise…
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CLINICAL_TRIALS trial_result · 2009-12-31Clinical Trial Update: Dexamethasone to Treat Acute Chest Syndrome in People With Sickle Cell Disease [Phase 3]
Phase 3 trial evaluating dexamethasone for acute chest syndrome in people with sickle cell disease was terminated, with results posted in 20…