Biphenotypic Leukemia

• CLINICAL_TRIALS trial_result · 2026-04-15
  Clinical Trial Update: Venetoclax in Combination With Decitabine and Cedazuridine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]

  A Phase 2 clinical trial update evaluating a combination of venetoclax, decitabine, and cedazuridine for relapsed or refractory acute myeloi…

• CLINICAL_TRIALS research · 2025-12-17
  Clinical Trial Update: Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome [Phase 1, Phase 2]

  A phase 1/2 clinical trial at MD Anderson is evaluating a quadruplet regimen of cladribine, idarubicin, cytarabine, and quizartinib for newl…

• CLINICAL_TRIALS trial_result · 2025-11-03
  Clinical Trial Update: Omacetaxine and Venetoclax for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Harboring Mutant RUNX1 [Phase 1, Phase 2]

  This clinical trial update reports a Phase 1/2 study of the combination omacetaxine mepesuccinate and venetoclax in relapsed or refractory a…

• CLINICAL_TRIALS research · 2025-08-26
  Clinical Trial Update: Infusion of Expanded Cord Blood Cells in Addition to Single Cord Blood Transplant in Treating Patients With Acute Leukemia, Chronic Myeloid Leukemia, or Myelodysplastic Syndromes [Phase 2]

  Phase 2 trial update evaluating the infusion of expanded cord blood cells in addition to a single cord blood transplant for patients with ac…

• CLINICAL_TRIALS trial_result · 2025-08-06
  Clinical Trial Update: HLA-Mismatched Unrelated Donor Bone Marrow Transplantation With Post-Transplantation Cyclophosphamide [Phase 2]

  Phase 2 clinical trial evaluating HLA-mismatched unrelated donor bone marrow transplantation with post-transplant cyclophosphamide; the stud…

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• CLINICAL_TRIALS trial_result · 2025-06-04
  Clinical Trial Update: Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD [Phase 2]

  Phase 2 clinical trial assessing selective depletion of CD45RA+ T cells from allogeneic stem cell grafts to prevent graft-versus-host diseas…

• CLINICAL_TRIALS trial_result · 2025-03-07
  Clinical Trial Update: Umbilical Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With Hematologic Disease [Phase 2]

  Phase 2 trial evaluating an umbilical cord blood transplant regimen with cyclophosphamide, fludarabine, and total-body irradiation for hemat…

• CLINICAL_TRIALS trial_result · 2024-03-19
  Clinical Trial Update: Clofarabine, Idarubicin, Cytarabine, Vincristine Sulfate, and Dexamethasone in Treating Patients With Newly Diagnosed or Relapsed Mixed Phenotype Acute Leukemia [Phase 2]

  Phase 2 trial evaluating a multi-drug regimen (clofarabine, idarubicin, cytarabine, vincristine, and dexamethasone) in newly diagnosed or re…

• CLINICAL_TRIALS trial_result · 2023-08-01
  Clinical Trial Update: Ibrutinib in Preventing Acute Leukemia in Patients After Reduced-Intensity Conditioning and Stem Cell Transplant [Phase 2]

  Phase 2 trial evaluating ibrutinib to prevent acute leukemia after reduced-intensity conditioning and stem cell transplant.

• CLINICAL_TRIALS trial_result · 2023-06-29
  Clinical Trial Update: Filgrastim, Cladribine, Cytarabine, and Mitoxantrone With Sorafenib in Treating Patients With Newly-Diagnosed, Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome [Phase 1, Phase 2]

  Phase 1/2 clinical trial assessing a combination regimen including filgrastim, cladribine, cytarabine, mitoxantrone, and sorafenib in newly …

• CLINICAL_TRIALS trial_result · 2023-02-17
  Clinical Trial Update: Treosulfan, Fludarabine Phosphate, and Total-Body Irradiation in Treating Patients With Hematological Cancer Who Are Undergoing Umbilical Cord Blood Transplant [Phase 2]

  Phase 2 clinical trial evaluating treosulfan, fludarabine phosphate, and total-body irradiation as conditioning for umbilical cord blood tra…

• CLINICAL_TRIALS trial_result · 2023-01-31
  Clinical Trial Update: Tac, Mini-MTX, MMF Versus Tac, MTX for GVHD Prevention [Phase 3]

  Phase 3 trial comparing Tacrolimus plus mini-methotrexate versus Tacrolimus plus methotrexate for graft-versus-host disease prevention has c…

• CLINICAL_TRIALS trial_result · 2021-07-06
  Clinical Trial Update: Donor Umbilical Cord Blood Transplant With or Without Ex-vivo Expanded Cord Blood Progenitor Cells in Treating Patients With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, or Myelodysplastic Syndromes [Phase 2]

  Phase 2 trial evaluating donor umbilical cord blood transplant with or without ex-vivo expanded cord blood progenitor cells in patients with…

• CLINICAL_TRIALS trial_result · 2019-10-21
  Clinical Trial Update: Management of Platelet Transfusion Therapy in Patients With Blood Cancer or Treatment-Induced Thrombocytopenia [Phase 2]

  Phase 2 clinical trial assessing management of platelet transfusion therapy in patients with blood cancers or treatment-induced thrombocytop…

• CLINICAL_TRIALS trial_result · 2019-09-24
  Clinical Trial Update: Lirilumab and Azacitidine in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia [Phase 2]

  Phase 2 trial evaluating lirilumab with azacitidine in refractory or relapsed acute myeloid leukemia was terminated; results posted in 2019.

• CLINICAL_TRIALS trial_result · 2014-10-31
  Clinical Trial Update: A Study of Withdrawal of Immunosuppression and Donor Lymphocyte Infusions Following Allogeneic Transplant for Pediatric Hematologic Malignancies [Phase 2]

  Phase 2 trial evaluating withdrawal of immunosuppression and donor lymphocyte infusions after allogeneic transplant in pediatric hematologic…