Achalasia
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Standard Versus Oesophago-gastric Junction Complex Myotomy for Treatment naïve Type 2 Achalasia Patients [NA]
A clinical trial compares standard versus oesophago-gastric junction complex myotomy for treatment-naïve Type II achalasia. The study is cur…
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Botox or Botox With Esophageal Dilation in Patients With Achalasia [Phase 4]
Phase 4 clinical trial update investigating Botox injections with or without esophageal dilation for achalasia; currently enrolling by invit…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Mechanisms of Weight Loss in Patients Diagnosed With Achalasia
A Vanderbilt-led clinical trial update investigating the mechanisms of weight loss in patients with achalasia, currently enrolling by invita…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: VZV in the Enteric Nervous System: Pathogenesis and Consequences [Phase 4]
Phase 4 clinical trial sponsored by Vanderbilt University Medical Center is investigating Varicella Zoster Virus involvement in the enteric …
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Electrosurgical Modes for Endoscopic Submucosal Dissection in Peroral Endoscopic Esophageal Myotomy [Phase 3]
A Phase 3 clinical trial is evaluating electrosurgical modes for endoscopic submucosal dissection during peroral endoscopic esophageal myoto…
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CLINICAL_TRIALS research · 2025-04-25Clinical Trial Update: ARAT for Reflux Disease After Peroral Endoscopic Myotomy in Patients With Achalasia [NA]
This clinical trial update states that ARAT for reflux disease after peroral endoscopic myotomy in patients with achalasia is currently enro…
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: Per-Oral Endoscopic Myotomy for Esophageal Swallowing Disorders [NA]
The trial evaluating Per-Oral Endoscopic Myotomy for achalasia has been terminated.
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: Risk Factors for Sub Mucosal Fibrosis During Achalasia Cardia: A Prospective Study
A prospective study investigating risk factors for submucosal fibrosis in patients with achalasia.
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CLINICAL_TRIALS research · 2024-12-03Clinical Trial Update: POEM-F for Achalasia International Study [NA]
This clinical trial update reports that POEM-F for achalasia is currently recruiting in an international study led by the Chinese University…
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Peroral Endoscopic Myotomy (POEM) for the Treatment of Achalasia
A completed clinical trial update evaluating Peroral Endoscopic Myotomy (POEM) for treating Achalasia.
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CLINICAL_TRIALS trial_result · 2024-07-10Clinical Trial Update: redoPOEM : Failure of a First POEM
This clinical trial update reports on redoPOEM procedures after failure of an initial POEM for achalasia and discusses the observed outcomes…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Development of Endoscopic Treatment for Achalasia [NA]
An ongoing clinical trial sponsored by Karolinska Institutet is evaluating an endoscopic treatment for achalasia; the study is currently act…
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CLINICAL_TRIALS withdrawal · 2021-11-17Clinical Trial Update: Assessing the Efficacy of Steroid Treatment of Achalasia [Phase 4]
Phase 4 clinical trial assessing steroid treatment for achalasia was withdrawn.
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CLINICAL_TRIALS trial_result · 2021-05-04Clinical Trial Update: Study of IW-1701, A Stimulator of Soluble Guanylate Cyclase (sGC), in Patients With Type I or II Achalasia [Phase 2]
Phase 2 trial of IW-1701 (an sGC stimulator) in Achalasia was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2020-01-18Clinical Trial Update: Single-Versus Multiple-dose Antimicrobial Prophylaxis for Peroral Endoscopic Myotomy in Achalasia [Phase 3]
Phase 3 clinical trial evaluating single- versus multiple-dose antimicrobial prophylaxis for Peroral Endoscopic Myotomy in achalasia.
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CLINICAL_TRIALS trial_result · 2019-11-26Clinical Trial Update: Post Operative Pain Control of POEM Procedure [Phase 4]
Phase 4 clinical trial update on postoperative pain control for the POEM procedure in achalasia patients.
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CLINICAL_TRIALS research · 2018-06-06Clinical Trial Update: Epidermoid Cancer Development in Esophageal Achalasia
This clinical trial update notes a possible development of epidermoid (esophageal squamous cell) carcinoma in individuals with esophageal ac…
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CLINICAL_TRIALS research · 2018-03-01Clinical Trial Update: POEM: Long vs Short Myotomy for Achalasia. RCT [NA]
This entry provides an update on a randomized trial comparing long versus short myotomy for achalasia (POEM); no results or current status a…
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Efficacy & Safety of Submucosal Endoscopic Myotomy With Mucosal Flap (SEMF) in the Treatment of Patients With Achalasia [NA]
Clinical trial results for Submucosal Endoscopic Myotomy With Mucosal Flap (SEMF) showing efficacy and safety for treating achalasia in comp…
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CLINICAL_TRIALS trial_result · 2017-05-01Clinical Trial Update: Per-Oral Endoscopic Myotomy (P.O.E.M.) for Treatment of Esophageal Motility Disorders [NA]
Clinical trial update indicating completion of a POEM (per-oral endoscopic myotomy) study for esophageal motility disorders, including achal…
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CLINICAL_TRIALS trial_result · 2017-04-12Clinical Trial Update: Laparoscopy Heller Myotomy With Fundoplication Associated Versus Peroral Endoscopic Myotomy (POEM) [NA]
Clinical trial comparing laparoscopic Heller myotomy with fundoplication versus peroral endoscopic myotomy (POEM) for achalasia; trial statu…
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CLINICAL_TRIALS withdrawal · 2017-04-10Clinical Trial Update: Correlation of High Resolution Esophageal Manometry With Symptoms
A clinical trial investigating the correlation between high-resolution esophageal manometry and patient symptoms has been withdrawn, involvi…
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CLINICAL_TRIALS research · 2017-02-20Clinical Trial Update: Peroral Endoscopic Myotomy (POEM) For The Treatment Of Achalasia: A Registry
The entry is a registry record evaluating peroral endoscopic myotomy (POEM) for the treatment of achalasia, with an unknown current status.
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CLINICAL_TRIALS trial_result · 2016-12-12Clinical Trial Update: Clinical Outcomes of Peroral Endoscopic Myotomy [NA]
This document reports an update on the clinical outcomes of Peroral Endoscopic Myotomy (POEM) for achalasia. The trial status is not disclos…
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CLINICAL_TRIALS trial_result · 2016-10-31Clinical Trial Update: The Role That Peroral Endoscopic Myotomy (POEM) Could Play in the Treatment of Achalasia [NA]
This clinical trial update outlines how peroral endoscopic myotomy (POEM) could be used to treat achalasia, referencing a Mayo Clinic study.…