Achalasia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: PREcision MEDicine In Achalasia (PREMEDIA) [Phase 3]
Phase 3 PREcision MEDicine In Achalasia (PREMEDIA) trial for Type I and Type II achalasia is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Artificial Intelligence-Guided Detection of Blood Vessels to Enhance Safety in Third-Space Endoscopic Procedures [NA]
A clinical trial in India is evaluating AI-guided detection of blood vessels to improve safety during third-space endoscopic procedures; it …
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: PRospective Registry of Esophageal Motility
This item notes a prospective registry study on esophageal motility that is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Clinical Outcomes, Safety, and Effectiveness of Speedboat UltraSlim™ in Per-Oral Endoscopic Myotomy (POEM)
An ongoing clinical trial evaluating the safety, effectiveness, and overall outcomes of using Speedboat UltraSlim during per-oral endoscopic…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Disposable Endoscope Platform in Third Space Endoscopic Procedures
Registry entry for a disposable endoscope platform being evaluated for third-space endoscopic procedures. The study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: POEM Trial: Multi-center Study Comparing Endoscopic Pneumodilation and Per Oral Endoscopic Myotomy (POEM) [NA]
This clinical trial update notes the completion of a multi-center study comparing endoscopic pneumodilation and Per Oral Endoscopic Myotomy …
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Achalasia and Dysplasia [NA]
KU Leuven conducted a trial on dysplasia in longstanding achalasia and its relation to food stasis. The study status is completed.
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: The Impact of Anesthetics on FLIP [NA]
A Baylor Research Institute clinical trial is investigating how anesthetics affect FLIP measurements in esophageal disorders, with enrollmen…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Serum Anti-enteric Neuronal Antibodies in Patients With Achalasia and Their Association With Clinical Profiles
A completed clinical study evaluated serum anti-enteric neuronal antibodies in patients with achalasia and examined how antibody presence re…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Effectiveness of Methods for Pyloric Drainage in esophagecTomY: Botox vs. Pyloromyotomy [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial at The Cleveland Clinic evaluating botox injections versus pyloromyotomy for pyloric drainage after esophag…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Per-Oral Endoscopic Myotomy (POEM) for the Treatment of Achalasia, Database Repository
A clinical trial is evaluating per-oral endoscopic myotomy (POEM) for achalasia and is currently enrolling by invitation.
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Safety and Efficacy of a Novel SpydrBlade Flexible Bipolar in POEM [NA]
A clinical trial update describes ongoing evaluation of the SpydrBlade Flexible Bipolar device for peroral endoscopic myotomy (POEM) in pati…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Prospective Evaluation of the Clinical Utility of Peroral Endoscopic Myotomy for Gastrointestinal Motility Disorders
ClinicalTrials.gov shows a prospective study evaluating the clinical utility of peroral endoscopic myotomy (POEM) across several GI motility…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Minimally Invasive Surgery of the Gastro-esophageal Junction
An update on a clinical trial evaluating minimally invasive surgery at the gastro-esophageal junction, with status ACTIVE_NOT_RECRUITING and…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Corticosteroid Effect on Achalasia Variant EGJOO [EARLY_Phase 1]
This clinical trial update describes an EARLY Phase 1 study evaluating the effect of corticosteroids on the achalasia variant Esophagogastri…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Metabolic Changes Associated With Weight Gain After Treatment of Achalasia
This clinical trial investigates metabolic changes associated with weight gain after treatment for achalasia. It is currently not recruiting…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Comparison of Conventional and Short Submucosal Tunnel Techniques in Type II Achalasia [NA]
A clinical trial comparing conventional and short submucosal tunnel techniques in Type II achalasia is currently NOT_YET_RECRUITING.
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Comparative Study of Per-oral Endoscopic Myotomy (POEM) in Treatment - naïve Achalasia Patients Versus Patients With Previous Pneumatic Dilation [NA]
This clinical trial compares outcomes of per-oral endoscopic myotomy (POEM) in treatment-naïve achalasia patients versus those with prior pn…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Outcome Analysis of POEM and Endoluminal Therapies [NA]
This clinical trial update notes ongoing enrollment and planned outcome analyses for POEM and endoluminal therapies in conditions including …
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Comprehensive Esophageal Diagnostics Study [Phase 4]
A Phase 4 clinical trial sponsored by Emory University is investigating comprehensive esophageal diagnostics in people with achalasia, and i…
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: Sling-Fiber Preservation POEM vs. Conventional POEM for Reducing Post-POEM GERD [NA]
A clinical trial comparing Sling-Fiber Preservation POEM versus Conventional POEM to reduce post-POEM GERD, sponsored by the University of C…
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: POEM- Peroral Endoscopic Myotomy for Esophageal Motility Disorders [NA]
Completed clinical trial evaluating peroral endoscopic myotomy (POEM) for achalasia, an esophageal motility disorder.
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Comparison of Balloon Dilatation and Per Oral Endoscopic Myotomy in Children With Achalasia Cardia [NA]
This clinical trial investigates balloon dilatation versus per oral endoscopic myotomy (POEM) in children with achalasia cardia and is not y…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Evolution of the Chicago Classification: Bridging Physiology and Mechanics [NA]
Northwestern University-sponsored clinical trial exploring the evolution of the Chicago Classification for esophageal motility disorders, cu…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: INCIDENCE, PREVALENCE AND OVERALL RISK OF ESOPHAGEAL CANCER IN ACHALASIA: A PROPENSITY-MATCHED POPULATION-BASED STUDY FROM A LARGE MULTICENTER DATABASE
A large multicenter, propensity-matched study analyzes the incidence, prevalence, and overall risk of esophageal cancer in patients with ach…