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CLINICAL_TRIALS research · 2025-08-17

Clinical Trial Update: Combination Study of Guadecitabine/ASTX727 and Pembrolizumab [Phase 1]

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Summary

A Phase 1 trial evaluating the safety of combining guadecitabine and ASTX727 with pembrolizumab in non-small cell lung cancer, currently recruiting.

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Diseases / indications

Drugs mentioned

  • ASTX727 (cedazuridine/decitabine)
  • Guadecitabine (guadecitabine)
  • Pembrolizumab (pembrolizumab)

Snippet

Sponsor: Royal Marsden NHS Foundation Trust | Conditions: Non Small Cell Lung Cancer | Phase 1 | Status: RECRUITING