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CLINICAL_TRIALS research · 2025-08-26

Clinical Trial Update: An Open Label Phase 2 Study of Total Neoadjuvant Therapy (TNT) Consisting of FLOT With Pembrolizumab and Short Radiation for Patients With Locally Advanced Gastroesophageal Junction Adenocarcinoma [Phase 2]

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Summary

An open-label Phase 2 trial evaluating total neoadjuvant therapy with FLOT chemotherapy plus pembrolizumab and short radiation for locally advanced gastroesopha…

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Diseases / indications

Drugs mentioned

  • 5-Fluorouracil (5-FU)
  • DOCETAXEL (DOCETAXEL)
  • Leucovorin (folinic acid)
  • OXALIPLATIN (Oxaliplatin)
  • Pembrolizumab (pembrolizumab)

Snippet

Sponsor: National Cancer Center Hospital East | Conditions: Gastroesophageal Junction (GEJ) Adenocarcinoma | Phase 2 | Status: RECRUITING