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CLINICAL_TRIALS research · 2025-09-08

Clinical Trial Update: Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation [Phase 2]

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Summary

Clinical trial update describing a Phase 2 study of adding irinotecan to the FOLFOX regimen after radiation therapy for locally advanced rectal cancer to improv…

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Diseases / indications

Drugs mentioned

  • 5-Fluorouracil (5-FU)
  • Irinotecan (Irinotecan)
  • Leucovorin (folinic acid)
  • OXALIPLATIN (Oxaliplatin)

Snippet

Sponsor: Alliance for Clinical Trials in Oncology | Conditions: Locally Advanced Rectal Carcinoma, Stage II Rectal Cancer AJCC v8 | Phase 2 | Status: ACTIVE_NOT_RECRUITING