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A Phase 2 Study to Assess the Safety and Efficacy of Cobimetinib in Refractory Langerhans Cell Histiocytosis, LCH-Associated Neurodegenerative Disease, and Other Histiocytic Disorders.

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Record identity and dates

Source
ClinicalTrials.gov
Source record ID
NCT04079179
Title field or adapter rule
protocolSection.identificationModule.officialTitle
Ingested At
2026-04-25T22:27:17.426615+00:00
Published At
2025-09-18T00:00:00+00:00
Record Updated At
2025-09-18
Timestamp Basis
source retrieval time was not retained by the feed adapter
Date limitation
source retrieval time was not retained by the feed adapter

Fields recorded by this source

protocolSection.conditionsModule.conditions
["Langerhan\u0027s Cell Histiocytosis", "Juvenile Xanthogranuloma", "Erdheim-Chester Disease", "Rosai Dorfman Disease", "Neuro-Degenerative Disease", "Histiocytic Sarcoma", "Histiocytic Disorders, Malignant"]
protocolSection.statusModule.lastUpdatePostDateStruct.date
"2025-09-18"
protocolSection.identificationModule.nctId
"NCT04079179"
protocolSection.identificationModule.officialTitle
"A Phase 2 Study to Assess the Safety and Efficacy of Cobimetinib in Refractory Langerhans Cell Histiocytosis, LCH-Associated Neurodegenerative Disease, and Other Histiocytic Disorders."
protocolSection.statusModule.overallStatus
"RECRUITING"
protocolSection.designModule.phases
["PHASE2"]
protocolSection.statusModule.resultsFirstPostDateStruct.date
""

Study condition terms

  • Langerhan's Cell Histiocytosis (protocolSection.conditionsModule.conditions)
  • Juvenile Xanthogranuloma (protocolSection.conditionsModule.conditions)
  • Erdheim-Chester Disease (protocolSection.conditionsModule.conditions)
  • Rosai Dorfman Disease (protocolSection.conditionsModule.conditions)
  • Neuro-Degenerative Disease (protocolSection.conditionsModule.conditions)
  • Histiocytic Sarcoma (protocolSection.conditionsModule.conditions)
  • Histiocytic Disorders, Malignant (protocolSection.conditionsModule.conditions)

Intervention details are not present in the imported fields for this record. No drug-condition relationship is inferred from co-listing.

This index keeps the source fields it imported; it may not contain the complete original record. Verify wording and context in the linked source.