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CLINICAL_TRIALS research · 2025-09-25

Clinical Trial Update: Clinical Trial to Evaluate the Safety and Immunogenicity of a Priming Regimen of 426c.Mod.Core-C4b Followed by HxB2.WT.Core-C4b Boosts, Both Adjuvanted With 3M-052 AF + Alum, in Adult Participants Without HIV and in Overall Good Health [Phase 1]

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Summary

Phase 1 clinical trial evaluating the safety and immunogenicity of a prime-boost HIV vaccine regimen (426c.Mod.Core-C4b prime followed by HxB2.WT.Core-C4b boost…

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Diseases / indications

Drugs mentioned

  • 3M-052 AF (TLR7/8 agonist adjuvant)
  • 426c.Mod.Core-C4b
  • Alum (aluminum-based adjuvant)
  • HxB2.WT.Core-C4b

Snippet

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) | Conditions: HIV | Phase 1 | Status: RECRUITING