Catalyst Wire Dossier Catalyst Wire Dossier
CLINICAL_TRIALS research · 2025-09-29

Clinical Trial Update: CYFIP1 and PKM2 Synergistically Regulate ROS and Glycolysis in Colorectal Cancer Through the AKT/mTOR/HIF-1α Cascad

View source ↗

Summary

A completed mechanistic study in colorectal cancer examining how CYFIP1 and PKM2 jointly regulate reactive oxygen species and glycolysis through the AKT/mTOR/HI…

Upgrade for the full analysis, importance score, and drug timeline.

Diseases / indications

Snippet

Sponsor: hui hou | Conditions: Colorectal Cancer (CRC), Specimens Are to be Collected From Subjects Who Are Having or Have Had a Fluid or Tissue Removed, a Biopsy or a Blood or Bone Marrow Draw | Status: COMPLETED