Clinical Trial Update: A Study of Ponatinib With Chemotherapy in Children, Teenagers, and Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia [Phase 1, Phase 2]

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Summary

A Phase 1/Phase 2 study evaluating ponatinib with chemotherapy in children, teenagers, and adults with Philadelphia chromosome–positive ALL, Ph+ MPAL, or Ph-lik…

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Diseases / indications

• Philadelphia Chromosome-like Acute Lymphoblastic Leukemia
• Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia
• Philadelphia Chromosome-positive Mixed Phenotype Acute Leukemia

Drugs mentioned

• Ponatinib (Iclusig) (ponatinib)

Snippet

Sponsor: Takeda | Conditions: Pediatric Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ALL), Ph+ Mixed Phenotype Acute Leukemia (MPAL) | Phase 1, Phase 2 | Status: TERMINATED | Results posted: 2025-01-15