A Phase 1, Open-Label, Multicenter Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer

This page presents selected fields from the linked source record. It does not add a medical interpretation.

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Record identity and dates

Source

ClinicalTrials.gov

Source record ID

NCT05519449

Title field or adapter rule

{'original_value': 'A Phase 1, Open-Label, Multicenter Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer', 'source_field': 'protocolSection.identificationModule.officialTitle'}

Ingested At

2026-11-01T01:03:06.150460+00:00

Published At

2026-10-29T00:00:00+00:00

Record Updated At

2026-10-29

Source Retrieved At

2026-11-01T01:03:05.968908+00:00

Timestamp Basis

ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Date limitation

ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Fields recorded by this source

protocolSection.conditionsModule.conditions

["Prostate Cancer", "Metastatic Castration-resistant Prostate Cancer", "Castration Resistant Prostatic Cancer"]

protocolSection.statusModule.lastUpdatePostDateStruct

{"date": "2026-10-29", "type": "ACTUAL"}

protocolSection.identificationModule.nctId

"NCT05519449"

protocolSection.identificationModule.officialTitle

"A Phase 1, Open-Label, Multicenter Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer"

protocolSection.statusModule.overallStatus

"RECRUITING"

protocolSection.designModule.phases

["PHASE1"]

protocolSection.statusModule.resultsFirstPostDateStruct

null

Study condition terms

• Prostate Cancer (protocolSection.conditionsModule.conditions)
• Metastatic Castration-resistant Prostate Cancer (protocolSection.conditionsModule.conditions)
• Castration Resistant Prostatic Cancer (protocolSection.conditionsModule.conditions)

Interventions recorded in this study

• {'armGroupLabels': ['Backfill Expansion', 'Combination Expansion', 'Dose Escalation', 'Monotherapy Expansion Parts A - D'], 'description': 'JANX007 is dosed via IV in a 21- or 28-day cycle.', 'name': 'JANX007', 'type': 'BIOLOGICAL'} (protocolSection.armsInterventionsModule.interventions[])
• {'armGroupLabels': ['Combination Expansion'], 'description': 'Darolutamide is dosed via oral tablets', 'name': 'Darolutamide', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])

An intervention appearing in a study record does not establish an effect or an approved use.

Drug names recorded in this source

• Darolutamide (protocolSection.armsInterventionsModule.interventions[].name)

A recorded drug name is not by itself an indication or a condition-specific relationship.

This index keeps the source fields it imported; it may not contain the complete original record. Verify wording and context in the linked source.