Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder

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Record identity and dates

Source

ClinicalTrials.gov

Source record ID

NCT03065335

Title field or adapter rule

{'original_value': 'Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder', 'source_field': 'protocolSection.identificationModule.officialTitle'}

Ingested At

2026-10-31T23:27:37.251382+00:00

Published At

2026-10-29T00:00:00+00:00

Record Updated At

2026-10-29

Source Retrieved At

2026-10-31T22:19:07.580396+00:00

Timestamp Basis

ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Date limitation

ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Fields recorded by this source

protocolSection.conditionsModule.conditions

["Healthy Volunteer", "Major Depressive Disorder", "Depression"]

protocolSection.statusModule.lastUpdatePostDateStruct

{"date": "2026-10-29", "type": "ACTUAL"}

protocolSection.identificationModule.nctId

"NCT03065335"

protocolSection.identificationModule.officialTitle

"Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder"

protocolSection.statusModule.overallStatus

"RECRUITING"

protocolSection.designModule.phases

["PHASE1"]

protocolSection.statusModule.resultsFirstPostDateStruct

null

Study condition terms

• Healthy Volunteer (protocolSection.conditionsModule.conditions)
• Major Depressive Disorder (protocolSection.conditionsModule.conditions)
• Depression (protocolSection.conditionsModule.conditions)

Interventions recorded in this study

• {'armGroupLabels': ['Metabolites Substudy', 'Phase II, Arm 1', 'Phase II, Arm 1b', 'Phase III'], 'description': 'N-methyl-D-aspartate (NMDA) glutamate receptor (NMDA-R) antagonist', 'name': 'Ketamine', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])
• {'armGroupLabels': ['Phase II, Arm 2', 'Phase II, Arm 2b'], 'description': 'Placebo comparator', 'name': 'Placebo', 'type': 'OTHER'} (protocolSection.armsInterventionsModule.interventions[])
• {'armGroupLabels': ['Phase I', 'Phase II, Arm 1', 'Phase II, Arm 1b', 'Phase II, Arm 2', 'Phase II, Arm 2b'], 'description': 'TMS-Cobot TS MV \\[Axilum Robotics\\] robotic arm for spatial positioning and orientation of the TMS coil', 'name': 'Cobot TS MV robotic arm for TMS', 'type': 'DEVICE'} (protocolSection.armsInterventionsModule.interventions[])
• {'armGroupLabels': ['Phase III'], 'description': 'The Neu-rOptics PLRTM-3000 Pupillometer will use quantitative infrared technology to objectively and accurately measure pupil size and dynamics.', 'name': 'NeurOptics PLRTM-30000 Pupillometer', 'type': 'DEVICE'} (protocolSection.armsInterventionsModule.interventions[])

An intervention appearing in a study record does not establish an effect or an approved use.

Drug names recorded in this source

• Ketamine (protocolSection.armsInterventionsModule.interventions[].name)

A recorded drug name is not by itself an indication or a condition-specific relationship.

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