MATCH Treatment Subprotocol T: GDC-0449 (Vismodegib) in Patients With Tumors (Except Basal Cell Skin Carcinoma) With Smoothened (SMO) or Patched 1 (PTCH1) Mutations

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Record identity and dates

Source

ClinicalTrials.gov

Source record ID

NCT06357988

Title field or adapter rule

{'original_value': 'MATCH Treatment Subprotocol T: GDC-0449 (Vismodegib) in Patients With Tumors (Except Basal Cell Skin Carcinoma) With Smoothened (SMO) or Patched 1 (PTCH1) Mutations', 'source_field': 'protocolSection.identificationModule.officialTitle'}

Ingested At

2026-10-31T23:27:36.706040+00:00

Published At

2026-04-21T00:00:00+00:00

Record Updated At

2026-10-16

Results Posted At

2026-04-21

Source Retrieved At

2026-10-31T22:19:02.163121+00:00

Timestamp Basis

ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Date limitation

ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Fields recorded by this source

protocolSection.conditionsModule.conditions

["Advanced Lymphoma", "Advanced Malignant Solid Neoplasm", "Hematopoietic and Lymphatic System Neoplasm", "Refractory Lymphoma", "Refractory Malignant Solid Neoplasm", "Refractory Multiple Myeloma"]

protocolSection.statusModule.lastUpdatePostDateStruct

{"date": "2026-10-16", "type": "ACTUAL"}

protocolSection.identificationModule.nctId

"NCT06357988"

protocolSection.identificationModule.officialTitle

"MATCH Treatment Subprotocol T: GDC-0449 (Vismodegib) in Patients With Tumors (Except Basal Cell Skin Carcinoma) With Smoothened (SMO) or Patched 1 (PTCH1) Mutations"

protocolSection.statusModule.overallStatus

"ACTIVE_NOT_RECRUITING"

protocolSection.designModule.phases

["PHASE2"]

protocolSection.statusModule.resultsFirstPostDateStruct

{"date": "2026-04-21", "type": "ACTUAL"}

Study condition terms

• Advanced Lymphoma (protocolSection.conditionsModule.conditions)
• Advanced Malignant Solid Neoplasm (protocolSection.conditionsModule.conditions)
• Hematopoietic and Lymphatic System Neoplasm (protocolSection.conditionsModule.conditions)
• Refractory Lymphoma (protocolSection.conditionsModule.conditions)
• Refractory Malignant Solid Neoplasm (protocolSection.conditionsModule.conditions)
• Refractory Multiple Myeloma (protocolSection.conditionsModule.conditions)

Interventions recorded in this study

• {'armGroupLabels': ['Treatment (Vismodegib)'], 'description': 'Undergo tumor biopsy', 'name': 'Biopsy Procedure', 'type': 'PROCEDURE'} (protocolSection.armsInterventionsModule.interventions[])
• {'armGroupLabels': ['Treatment (Vismodegib)'], 'description': 'Undergo blood sample collection', 'name': 'Biospecimen Collection', 'type': 'PROCEDURE'} (protocolSection.armsInterventionsModule.interventions[])
• {'armGroupLabels': ['Treatment (Vismodegib)'], 'description': 'Undergo echocardiography', 'name': 'Echocardiography Test', 'type': 'PROCEDURE'} (protocolSection.armsInterventionsModule.interventions[])
• {'armGroupLabels': ['Treatment (Vismodegib)'], 'description': 'Undergo nuclear study', 'name': 'Radionuclide Imaging', 'type': 'PROCEDURE'} (protocolSection.armsInterventionsModule.interventions[])
• {'armGroupLabels': ['Treatment (Vismodegib)'], 'description': 'Given PO', 'name': 'Vismodegib', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])

An intervention appearing in a study record does not establish an effect or an approved use.

Drug names recorded in this source

• Vismodegib (protocolSection.armsInterventionsModule.interventions[].name)

A recorded drug name is not by itself an indication or a condition-specific relationship.

This index keeps the source fields it imported; it may not contain the complete original record. Verify wording and context in the linked source.