Disentangling Microbiome Engraftment by Multi-omics of the Gut Ecosystem During Fecal Transplant

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Record identity and dates

Source

ClinicalTrials.gov

Source record ID

NCT06992453

Title field or adapter rule

{'original_value': 'Disentangling Microbiome Engraftment by Multi-omics of the Gut Ecosystem During Fecal Transplant', 'source_field': 'protocolSection.identificationModule.officialTitle'}

Ingested At

2026-10-31T23:27:36.521087+00:00

Published At

2026-10-26T00:00:00+00:00

Record Updated At

2026-10-26

Source Retrieved At

2026-10-31T22:18:58.295941+00:00

Timestamp Basis

ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Date limitation

ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Fields recorded by this source

protocolSection.conditionsModule.conditions

["Recurrent C. Difficile (rCDI)", "Ulcerative Colitis (UC)", "Metabolic Syndrome (MetS)"]

protocolSection.statusModule.lastUpdatePostDateStruct

{"date": "2026-10-26", "type": "ACTUAL"}

protocolSection.identificationModule.nctId

"NCT06992453"

protocolSection.identificationModule.officialTitle

"Disentangling Microbiome Engraftment by Multi-omics of the Gut Ecosystem During Fecal Transplant"

protocolSection.statusModule.overallStatus

"RECRUITING"

protocolSection.designModule.phases

["NA"]

protocolSection.statusModule.resultsFirstPostDateStruct

null

Study condition terms

• Recurrent C. Difficile (rCDI) (protocolSection.conditionsModule.conditions)
• Ulcerative Colitis (UC) (protocolSection.conditionsModule.conditions)
• Metabolic Syndrome (MetS) (protocolSection.conditionsModule.conditions)

Interventions recorded in this study

• {'armGroupLabels': ['Metabolic syndrome (MetS) Cohort', 'Recurrent C. difficile infection (rCDI) Cohort', 'Ulcerative Colitis (UC) Cohort'], 'description': 'Patients will receive a first donor FMT by colonoscopy, after a pre-conditioning with vancomycin and neomycin + bacitracin for 3 days, because data from our group show that pre-FMT antibiotics are associated with higher rates of microbial engraftment. Then they will receive two cycles, respectively after 3 and 7 days after colonoscopy - FMT, of frozen donor FMT capsules (15 capsules b.i.d. per 3 days). Patients will always receive feces from the same donor.', 'name': 'Fecal microbiota transplantation (FMT)', 'type': 'OTHER'} (protocolSection.armsInterventionsModule.interventions[])

An intervention appearing in a study record does not establish an effect or an approved use.

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