Phase 1 Study to Evaluate [18F]ACI-15916 as a Potential PET Radioligand for Imaging α-synuclein Deposits in the Brain of Patients With Suspected α-synuclein Pathology Compared With Healthy Volunteers

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Record identity and dates

Source

ClinicalTrials.gov

Source record ID

NCT06891703

Title field or adapter rule

{'original_value': 'Phase 1 Study to Evaluate [18F]ACI-15916 as a Potential PET Radioligand for Imaging α-synuclein Deposits in the Brain of Patients With Suspected α-synuclein Pathology Compared With Healthy Volunteers', 'source_field': 'protocolSection.identificationModule.officialTitle'}

Ingested At

2026-10-31T23:27:33.555530+00:00

Published At

2026-10-28T00:00:00+00:00

Record Updated At

2026-10-28

Source Retrieved At

2026-10-31T22:18:37.902788+00:00

Timestamp Basis

ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Date limitation

ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Fields recorded by this source

protocolSection.conditionsModule.conditions

["Parkinson\u0027s Disease (PD)", "Multiple System Atrophy (MSA)", "Dementia With Lewy Bodies (DLB)"]

protocolSection.statusModule.lastUpdatePostDateStruct

{"date": "2026-10-28", "type": "ACTUAL"}

protocolSection.identificationModule.nctId

"NCT06891703"

protocolSection.identificationModule.officialTitle

"Phase 1 Study to Evaluate [18F]ACI-15916 as a Potential PET Radioligand for Imaging \u03b1-synuclein Deposits in the Brain of Patients With Suspected \u03b1-synuclein Pathology Compared With Healthy Volunteers"

protocolSection.statusModule.overallStatus

"RECRUITING"

protocolSection.designModule.phases

["EARLY_PHASE1"]

protocolSection.statusModule.resultsFirstPostDateStruct

null

Study condition terms

• Parkinson's Disease (PD) (protocolSection.conditionsModule.conditions)
• Multiple System Atrophy (MSA) (protocolSection.conditionsModule.conditions)
• Dementia With Lewy Bodies (DLB) (protocolSection.conditionsModule.conditions)

Interventions recorded in this study

• {'armGroupLabels': ['Healthy volunteers', 'Participants with suspected α-synucleinopathies'], 'description': '\\[18F\\]ACI-15916 is an intravenously administered radioactive imaging agent being studied as a potential positron emitting radiopharmaceutical for in vivo imaging of α-synuclein deposits.', 'name': '[18F]ACI-15916', 'type': 'OTHER'} (protocolSection.armsInterventionsModule.interventions[])

An intervention appearing in a study record does not establish an effect or an approved use.

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