CLINICAL_TRIALS ClinicalTrials.gov record update

A Randomized Phase III Trial of Endocrine Therapy Plus Entinostat/Placebo in Patients With Hormone Receptor-Positive Advanced Breast Cancer

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Record identity and dates

Source: ClinicalTrials.gov
Source record ID: NCT02115282
Title field or adapter rule: {'original_value': 'A Randomized Phase III Trial of Endocrine Therapy Plus Entinostat/Placebo in Patients With Hormone Receptor-Positive Advanced Breast Cancer', 'source_field': 'protocolSection.identificationModule.officialTitle'}
Ingested At: 2026-10-31T23:27:30.773278+00:00
Published At: 2021-11-16T00:00:00+00:00
Record Updated At: 2026-10-22
Results Posted At: 2021-11-16
Source Retrieved At: 2026-10-31T22:18:24.976182+00:00
Timestamp Basis: ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter
Date limitation: ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Fields recorded by this source

protocolSection.conditionsModule.conditions: ["Anatomic Stage III Breast Cancer AJCC v8", "Anatomic Stage IV Breast Cancer AJCC v8", "Breast Adenocarcinoma", "HER2/Neu Negative", "Locally Advanced Breast Carcinoma", "Metastatic Breast Carcinoma", "Recurrent Breast Carcinoma"]
protocolSection.statusModule.lastUpdatePostDateStruct: {"date": "2026-10-22", "type": "ACTUAL"}
protocolSection.identificationModule.nctId: "NCT02115282"
protocolSection.identificationModule.officialTitle: "A Randomized Phase III Trial of Endocrine Therapy Plus Entinostat/Placebo in Patients With Hormone Receptor-Positive Advanced Breast Cancer"
protocolSection.statusModule.overallStatus: "ACTIVE_NOT_RECRUITING"
protocolSection.designModule.phases: ["PHASE3"]
protocolSection.statusModule.resultsFirstPostDateStruct: {"date": "2021-11-16", "type": "ACTUAL"}

Study condition terms

Interventions recorded in this study

{'armGroupLabels': ['Arm A (exemestane, entinostat)', 'Arm B (exemestane, placebo)'], 'description': 'Undergo collection of blood and archived tissue samples', 'name': 'Biospecimen Collection', 'type': 'PROCEDURE'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm A (exemestane, entinostat)', 'Arm B (exemestane, placebo)'], 'description': 'Undergo CT', 'name': 'Computed Tomography', 'type': 'PROCEDURE'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm A (exemestane, entinostat)'], 'description': 'Given PO', 'name': 'Entinostat', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm A (exemestane, entinostat)', 'Arm B (exemestane, placebo)'], 'description': 'Given PO', 'name': 'Exemestane', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm A (exemestane, entinostat)', 'Arm B (exemestane, placebo)'], 'description': 'Given PO', 'name': 'Goserelin', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm A (exemestane, entinostat)', 'Arm B (exemestane, placebo)'], 'description': 'Given SC', 'name': 'Goserelin Acetate', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm A (exemestane, entinostat)', 'Arm B (exemestane, placebo)'], 'description': 'Undergo MRI', 'name': 'Magnetic Resonance Imaging', 'type': 'PROCEDURE'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm B (exemestane, placebo)'], 'description': 'Given PO', 'name': 'Placebo Administration', 'type': 'OTHER'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm A (exemestane, entinostat)', 'Arm B (exemestane, placebo)'], 'description': 'Ancillary studies', 'name': 'Quality-of-Life Assessment', 'type': 'OTHER'} (protocolSection.armsInterventionsModule.interventions[])

An intervention appearing in a study record does not establish an effect or an approved use.

Drug names recorded in this source

A recorded drug name is not by itself an indication or a condition-specific relationship.

This index keeps the source fields it imported; it may not contain the complete original record. Verify wording and context in the linked source.