Prospective Observational Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

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Record identity and dates

Source

ClinicalTrials.gov

Source record ID

NCT03418961

Title field or adapter rule

{'original_value': 'Prospective Observational Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity', 'source_field': 'protocolSection.identificationModule.officialTitle'}

Ingested At

2026-10-31T23:27:30.107229+00:00

Published At

2026-10-28T00:00:00+00:00

Record Updated At

2026-10-28

Source Retrieved At

2026-10-31T22:18:24.976182+00:00

Timestamp Basis

ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Date limitation

ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Fields recorded by this source

protocolSection.conditionsModule.conditions

["Cardiotoxicity", "HER2/Neu Positive", "Metastatic Malignant Neoplasm in the Brain", "Recurrent Breast Carcinoma", "Stage IV Breast Cancer AJCC v6 and v7"]

protocolSection.statusModule.lastUpdatePostDateStruct

{"date": "2026-10-28", "type": "ACTUAL"}

protocolSection.identificationModule.nctId

"NCT03418961"

protocolSection.identificationModule.officialTitle

"Prospective Observational Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity"

protocolSection.statusModule.overallStatus

"RECRUITING"

protocolSection.designModule.phases

["PHASE3"]

protocolSection.statusModule.resultsFirstPostDateStruct

null

Study condition terms

• Cardiotoxicity (protocolSection.conditionsModule.conditions)
• HER2/Neu Positive (protocolSection.conditionsModule.conditions)
• Metastatic Malignant Neoplasm in the Brain (protocolSection.conditionsModule.conditions)
• Recurrent Breast Carcinoma (protocolSection.conditionsModule.conditions)
• Stage IV Breast Cancer AJCC v6 and v7 (protocolSection.conditionsModule.conditions)

Interventions recorded in this study

• {'armGroupLabels': ['Arm I (carvedilol)'], 'description': 'Given PO', 'name': 'Carvedilol', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])
• {'armGroupLabels': ['Arm I (carvedilol)', 'Arm II (no intervention)', 'Arm III (observation)'], 'description': 'Correlative studies', 'name': 'Laboratory Biomarker Analysis', 'type': 'OTHER'} (protocolSection.armsInterventionsModule.interventions[])
• {'armGroupLabels': ['Arm III (observation)'], 'description': 'Undergo observation', 'name': 'Patient Observation', 'type': 'OTHER'} (protocolSection.armsInterventionsModule.interventions[])

An intervention appearing in a study record does not establish an effect or an approved use.

Drug names recorded in this source

• Carvedilol (protocolSection.armsInterventionsModule.interventions[].name)

A recorded drug name is not by itself an indication or a condition-specific relationship.

This index keeps the source fields it imported; it may not contain the complete original record. Verify wording and context in the linked source.