CLINICAL_TRIALS ClinicalTrials.gov record update

A Phase 1a/b Study to Evaluate the Safety and Efficacy of OPB 201, an Autologous PReferentially Expressed Antigen of MElanoma (PRAME) T Cell Receptor (TCR) T Cell Therapy in Recurrent Endometrial and Platinum-resistant Ovarian Cancer.

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Record identity and dates

Source: ClinicalTrials.gov
Source record ID: NCT07664735
Title field or adapter rule: {'original_value': 'A Phase 1a/b Study to Evaluate the Safety and Efficacy of OPB 201, an Autologous PReferentially Expressed Antigen of MElanoma (PRAME) T Cell Receptor (TCR) T Cell Therapy in Recurrent Endometrial and Platinum-resistant Ovarian Cancer.', 'source_field': 'protocolSection.identificationModule.officialTitle'}
Ingested At: 2026-10-31T23:27:29.803197+00:00
Published At: 2026-10-26T00:00:00+00:00
Record Updated At: 2026-10-26
Source Retrieved At: 2026-10-31T22:18:13.198083+00:00
Timestamp Basis: ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter
Date limitation: ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

protocolSection.conditionsModule.conditions: ["Endometrial Cancer Recurrent", "Endometrial Cancer", "Advanced Endometrial Cancer", "Ovarian Cancer", "Ovarian Cancer Recurrent", "Platinum Resistant Ovarian Cancer", "Endometrial Cancers"]
protocolSection.statusModule.lastUpdatePostDateStruct: {"date": "2026-10-26", "type": "ACTUAL"}
protocolSection.identificationModule.nctId: "NCT07664735"
protocolSection.identificationModule.officialTitle: "A Phase 1a/b Study to Evaluate the Safety and Efficacy of OPB 201, an Autologous PReferentially Expressed Antigen of MElanoma (PRAME) T Cell Receptor (TCR) T Cell Therapy in Recurrent Endometrial and Platinum-resistant Ovarian Cancer."
protocolSection.statusModule.overallStatus: "RECRUITING"
protocolSection.designModule.phases: ["PHASE1"]
protocolSection.statusModule.resultsFirstPostDateStruct: null

{'armGroupLabels': ['OPB-201 Treatment Arm'], 'description': 'A multi-transgene autologous TCR T cell therapy with optimized alpha and beta chains of a TCR specific for a peptide derived from PRAME and a designed protein which enhances TCR T cell potency.', 'name': 'OPB-201', 'type': 'BIOLOGICAL'} (protocolSection.armsInterventionsModule.interventions[])

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