CLINICAL_TRIALS ClinicalTrials.gov record update

A Multicenter Randomized Open-Label Trial Evaluating ctDNA-Guided Interruption Versus Standard of Care Continuous Immune-Checkpoint Inhibitor (ICI) Therapy In Patients With Advanced/Metastatic Solid Tumors

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Record identity and dates

Source: ClinicalTrials.gov
Source record ID: NCT07689812
Title field or adapter rule: {'original_value': 'A Multicenter Randomized Open-Label Trial Evaluating ctDNA-Guided Interruption Versus Standard of Care Continuous Immune-Checkpoint Inhibitor (ICI) Therapy In Patients With Advanced/Metastatic Solid Tumors', 'source_field': 'protocolSection.identificationModule.officialTitle'}
Ingested At: 2026-10-31T23:27:29.730742+00:00
Published At: 2026-10-27T00:00:00+00:00
Record Updated At: 2026-10-27
Source Retrieved At: 2026-10-31T22:19:02.163121+00:00
Timestamp Basis: ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter
Date limitation: ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

protocolSection.conditionsModule.conditions: ["NSCLC (Advanced Non-small Cell Lung Cancer)", "NSCLC (Non-small Cell Lung Cancer)", "NSCLC (Non-small Cell Lung Carcinoma)", "NSCLC", "Melanoma (Skin Cancer)", "Melanoma (Skin) Stage IV", "CRC", "MSI High Colorectal Cancer", "DMMR Colorectal Cancer", "RCC, Renal Cell Cancer", "RCC", "Solid Tumors", "Metastatic Solid Tumors", "Advanced Solid Tumors", "Advanced Solid Tumors Cancer"]
protocolSection.statusModule.lastUpdatePostDateStruct: {"date": "2026-10-27", "type": "ACTUAL"}
protocolSection.identificationModule.nctId: "NCT07689812"
protocolSection.identificationModule.officialTitle: "A Multicenter Randomized Open-Label Trial Evaluating ctDNA-Guided Interruption Versus Standard of Care Continuous Immune-Checkpoint Inhibitor (ICI) Therapy In Patients With Advanced/Metastatic Solid Tumors"
protocolSection.statusModule.overallStatus: "NOT_YET_RECRUITING"
protocolSection.designModule.phases: ["NA"]
protocolSection.statusModule.resultsFirstPostDateStruct: null

{'armGroupLabels': ['SOC Continuous ICI', 'ctDNA-Guided Intermittent ICI'], 'description': 'The test is used to monitor for disease recurrence.', 'name': 'Signatera Genome ultra-sensitive ctDNA blood test', 'type': 'DEVICE'} (protocolSection.armsInterventionsModule.interventions[])

An intervention appearing in a study record does not establish an effect or an approved use.

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