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An Open-Label, Multicenter, Global Phase 2 Basket Study of Entrectinib for the Treatment of Patients With Locally Advanced or Metastatic Solid Tumors That Harbor NTRK1/2/3, ROS1, or ALK Gene Rearrangements

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Record identity and dates

Source
ClinicalTrials.gov
Source record ID
NCT02568267
Title field or adapter rule
{'original_value': 'An Open-Label, Multicenter, Global Phase 2 Basket Study of Entrectinib for the Treatment of Patients With Locally Advanced or Metastatic Solid Tumors That Harbor NTRK1/2/3, ROS1, or ALK Gene Rearrangements', 'source_field': 'protocolSection.identificationModule.officialTitle'}
Ingested At
2026-10-31T23:27:27.001221+00:00
Published At
2026-08-25T00:00:00+00:00
Record Updated At
2026-08-25
Source Retrieved At
2026-10-31T22:17:58.991924+00:00
Timestamp Basis
ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter
Date limitation
ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Fields recorded by this source

protocolSection.conditionsModule.conditions
["Breast Cancer", "Cholangiocarcinoma", "Colorectal Cancer", "Head and Neck Neoplasms", "Lymphoma, Large-Cell, Anaplastic", "Melanoma", "Neuroendocrine Tumors", "Non-Small Cell Lung Cancer", "Ovarian Cancer", "Pancreatic Cancer", "Papillary Thyroid Cancer", "Primary Brain Tumors", "Renal Cell Carcinoma", "Sarcomas", "Salivary Gland Cancers", "Adult Solid Tumor"]
protocolSection.statusModule.lastUpdatePostDateStruct
{"date": "2026-08-25", "type": "ACTUAL"}
protocolSection.identificationModule.nctId
"NCT02568267"
protocolSection.identificationModule.officialTitle
"An Open-Label, Multicenter, Global Phase 2 Basket Study of Entrectinib for the Treatment of Patients With Locally Advanced or Metastatic Solid Tumors That Harbor NTRK1/2/3, ROS1, or ALK Gene Rearrangements"
protocolSection.statusModule.overallStatus
"ACTIVE_NOT_RECRUITING"
protocolSection.designModule.phases
["PHASE2"]
protocolSection.statusModule.resultsFirstPostDateStruct
null

Study condition terms

  • Breast Cancer (protocolSection.conditionsModule.conditions)
  • Cholangiocarcinoma (protocolSection.conditionsModule.conditions)
  • Colorectal Cancer (protocolSection.conditionsModule.conditions)
  • Head and Neck Neoplasms (protocolSection.conditionsModule.conditions)
  • Lymphoma, Large-Cell, Anaplastic (protocolSection.conditionsModule.conditions)
  • Melanoma (protocolSection.conditionsModule.conditions)
  • Neuroendocrine Tumors (protocolSection.conditionsModule.conditions)
  • Non-Small Cell Lung Cancer (protocolSection.conditionsModule.conditions)
  • Ovarian Cancer (protocolSection.conditionsModule.conditions)
  • Pancreatic Cancer (protocolSection.conditionsModule.conditions)
  • Papillary Thyroid Cancer (protocolSection.conditionsModule.conditions)
  • Primary Brain Tumors (protocolSection.conditionsModule.conditions)
  • Renal Cell Carcinoma (protocolSection.conditionsModule.conditions)
  • Sarcomas (protocolSection.conditionsModule.conditions)
  • Salivary Gland Cancers (protocolSection.conditionsModule.conditions)
  • Adult Solid Tumor (protocolSection.conditionsModule.conditions)

Interventions recorded in this study

  • {'armGroupLabels': ['ALK- or ROS1-rearranged NSCLC', 'ALK-rearranged mCRC', 'ALK-rearranged other solid tumor', 'NTRK/1/2/3-rearranged mCRC', 'NTRK1/2/3-rearranged NSCLC', 'NTRK1/2/3-rearranged other solid tumor', 'ROS1-rearranged NSCLC', 'ROS1-rearranged mCRC', 'ROS1-rearranged other solid tumor'], 'description': 'TrkA/B/C, ROS1, and ALK inhibitor', 'name': 'Entrectinib', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])

An intervention appearing in a study record does not establish an effect or an approved use.

Drug names recorded in this source

  • Entrectinib (protocolSection.armsInterventionsModule.interventions[].name)

A recorded drug name is not by itself an indication or a condition-specific relationship.

This index keeps the source fields it imported; it may not contain the complete original record. Verify wording and context in the linked source.