CLINICAL_TRIALS ClinicalTrials.gov record update

A Phase III Randomized Trial of Dose Escalated Radiation in Locally Advanced Pancreas Cancer (LAPC) Patients (LAP100)

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Record identity and dates

Source: ClinicalTrials.gov
Source record ID: NCT06958328
Title field or adapter rule: {'original_value': 'A Phase III Randomized Trial of Dose Escalated Radiation in Locally Advanced Pancreas Cancer (LAPC) Patients (LAP100)', 'source_field': 'protocolSection.identificationModule.officialTitle'}
Ingested At: 2026-10-31T23:27:26.993775+00:00
Published At: 2026-08-25T00:00:00+00:00
Record Updated At: 2026-08-25
Source Retrieved At: 2026-10-31T22:17:58.991924+00:00
Timestamp Basis: ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter
Date limitation: ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Fields recorded by this source

protocolSection.conditionsModule.conditions: ["Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma", "Stage II Pancreatic Cancer AJCC v8", "Stage III Pancreatic Cancer AJCC v8", "Stage IV Pancreatic Cancer AJCC v8"]
protocolSection.statusModule.lastUpdatePostDateStruct: {"date": "2026-08-25", "type": "ACTUAL"}
protocolSection.identificationModule.nctId: "NCT06958328"
protocolSection.identificationModule.officialTitle: "A Phase III Randomized Trial of Dose Escalated Radiation in Locally Advanced Pancreas Cancer (LAPC) Patients (LAP100)"
protocolSection.statusModule.overallStatus: "RECRUITING"
protocolSection.designModule.phases: ["PHASE3"]
protocolSection.statusModule.resultsFirstPostDateStruct: null

Study condition terms

Interventions recorded in this study

{'armGroupLabels': ['Arm I (Options 1, 2, or 3)', 'Arm II (dose-escalated RT)'], 'description': 'Undergo tumor tissue biopsy', 'name': 'Biopsy Procedure', 'type': 'PROCEDURE'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm I (Options 1, 2, or 3)', 'Arm II (dose-escalated RT)'], 'description': 'Undergo blood sample collection', 'name': 'Biospecimen Collection', 'type': 'PROCEDURE'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm I (Options 1, 2, or 3)', 'Arm II (dose-escalated RT)'], 'description': 'Given capecitabine', 'name': 'Capecitabine', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm I (Options 1, 2, or 3)', 'Arm II (dose-escalated RT)'], 'description': 'Undergo CT or PET/CT', 'name': 'Computed Tomography', 'type': 'PROCEDURE'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm II (dose-escalated RT)'], 'description': 'Undergo dose-escalated radiation using intensity-modulated radiation therapy treatment planning', 'name': 'Dose-escalated Radiation Therapy', 'type': 'RADIATION'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm I (Options 1, 2, or 3)', 'Arm II (dose-escalated RT)'], 'description': 'Given fluorouracil', 'name': 'Fluorouracil', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm I (Options 1, 2, or 3)'], 'description': 'Given gemcitabine', 'name': 'Gemcitabine', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm I (Options 1, 2, or 3)'], 'description': 'Given irinotecan hydrochloride', 'name': 'Irinotecan Hydrochloride', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm I (Options 1, 2, or 3)'], 'description': 'Given liposomal irinotecan', 'name': 'Irinotecan Sucrosofate', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm I (Options 1, 2, or 3)'], 'description': 'Given leucovorin calcium', 'name': 'Leucovorin Calcium', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm I (Options 1, 2, or 3)', 'Arm II (dose-escalated RT)'], 'description': 'Undergo MRI', 'name': 'Magnetic Resonance Imaging', 'type': 'PROCEDURE'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm I (Options 1, 2, or 3)'], 'description': 'Given nab-paclitaxel', 'name': 'Nab-paclitaxel', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm I (Options 1, 2, or 3)'], 'description': 'Undergo observation', 'name': 'Observation Activity', 'type': 'OTHER'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm I (Options 1, 2, or 3)'], 'description': 'Given oxaliplatin', 'name': 'Oxaliplatin', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm I (Options 1, 2, or 3)', 'Arm II (dose-escalated RT)'], 'description': 'Undergo PET/CT', 'name': 'Positron Emission Tomography', 'type': 'PROCEDURE'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm I (Options 1, 2, or 3)', 'Arm II (dose-escalated RT)'], 'description': 'Ancillary studies', 'name': 'Questionnaire Administration', 'type': 'OTHER'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm I (Options 1, 2, or 3)'], 'description': 'Undergo standard radiation therapy', 'name': 'Radiation Therapy', 'type': 'RADIATION'} (protocolSection.armsInterventionsModule.interventions[])
{'armGroupLabels': ['Arm I (Options 1, 2, or 3)'], 'description': 'Undergo TTF', 'name': 'Tumor Treating Fields Therapy', 'type': 'PROCEDURE'} (protocolSection.armsInterventionsModule.interventions[])

An intervention appearing in a study record does not establish an effect or an approved use.

Drug names recorded in this source

A recorded drug name is not by itself an indication or a condition-specific relationship.

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