A Phase 1 Multiple Expansion Cohort Trial of MRTX1719 in Patients With Advanced Solid Tumors With Homozygous MTAP Deletion

This page presents selected fields from the linked source record. It does not add a medical interpretation.

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Record identity and dates

Source

ClinicalTrials.gov

Source record ID

NCT05245500

Title field or adapter rule

{'original_value': 'A Phase 1 Multiple Expansion Cohort Trial of MRTX1719 in Patients With Advanced Solid Tumors With Homozygous MTAP Deletion', 'source_field': 'protocolSection.identificationModule.officialTitle'}

Ingested At

2026-10-31T23:27:26.682452+00:00

Published At

2026-09-02T00:00:00+00:00

Record Updated At

2026-09-02

Source Retrieved At

2026-10-31T22:17:58.991924+00:00

Timestamp Basis

ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Date limitation

ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Fields recorded by this source

protocolSection.conditionsModule.conditions

["Mesothelioma", "Non Small Cell Lung Cancer", "Malignant Peripheral Nerve Sheath Tumors", "Solid Tumor", "Pancreatic Adenocarcinoma", "Advanced Solid Tumor"]

protocolSection.statusModule.lastUpdatePostDateStruct

{"date": "2026-09-02", "type": "ACTUAL"}

protocolSection.identificationModule.nctId

"NCT05245500"

protocolSection.identificationModule.officialTitle

"A Phase 1 Multiple Expansion Cohort Trial of MRTX1719 in Patients With Advanced Solid Tumors With Homozygous MTAP Deletion"

protocolSection.statusModule.overallStatus

"RECRUITING"

protocolSection.designModule.phases

["PHASE1"]

protocolSection.statusModule.resultsFirstPostDateStruct

null

Study condition terms

• Mesothelioma (protocolSection.conditionsModule.conditions)
• Non Small Cell Lung Cancer (protocolSection.conditionsModule.conditions)
• Malignant Peripheral Nerve Sheath Tumors (protocolSection.conditionsModule.conditions)
• Solid Tumor (protocolSection.conditionsModule.conditions)
• Pancreatic Adenocarcinoma (protocolSection.conditionsModule.conditions)
• Advanced Solid Tumor (protocolSection.conditionsModule.conditions)

Interventions recorded in this study

• {'armGroupLabels': ['Phase 1/1B', 'Phase 1b Sub-studies 1-4', 'Phase 1b Sub-study 5'], 'description': 'MRTX1719 is a potent PRMT5-MTA inhibitor. Specified dose on specified days', 'name': 'MRTX1719', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])

An intervention appearing in a study record does not establish an effect or an approved use.

Drug names recorded in this source

• MRTX1719 (protocolSection.armsInterventionsModule.interventions[].name)

A recorded drug name is not by itself an indication or a condition-specific relationship.

This index keeps the source fields it imported; it may not contain the complete original record. Verify wording and context in the linked source.