A Phase 1 First-in-human, Open-label Study Evaluating Safety, Pharmacokinetics, and Efficacy of ABBV-253 in Adult Subjects With Advanced Solid Tumors

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Record identity and dates

Source

ClinicalTrials.gov

Source record ID

NCT07807956

Title field or adapter rule

{'original_value': 'A Phase 1 First-in-human, Open-label Study Evaluating Safety, Pharmacokinetics, and Efficacy of ABBV-253 in Adult Subjects With Advanced Solid Tumors', 'source_field': 'protocolSection.identificationModule.officialTitle'}

Ingested At

2026-10-31T23:27:23.232233+00:00

Published At

2026-10-16T00:00:00+00:00

Record Updated At

2026-10-16

Source Retrieved At

2026-10-31T22:17:52.415050+00:00

Timestamp Basis

ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Date limitation

ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Fields recorded by this source

protocolSection.conditionsModule.conditions

["Advanced Solid Tumors", "Non-Small Cell Lung Cancer", "Colorectal Cancer", "Pancreatic Ductal Adenocarcinoma", "Gastric Cancer", "Gastroesophageal Junction Adenocarcinoma", "Biliary Tract Cancer", "Head and Neck Squamous Cell Carcinoma", "Ovarian Cancer"]

protocolSection.statusModule.lastUpdatePostDateStruct

{"date": "2026-10-16", "type": "ACTUAL"}

protocolSection.identificationModule.nctId

"NCT07807956"

protocolSection.identificationModule.officialTitle

"A Phase 1 First-in-human, Open-label Study Evaluating Safety, Pharmacokinetics, and Efficacy of ABBV-253 in Adult Subjects With Advanced Solid Tumors"

protocolSection.statusModule.overallStatus

"RECRUITING"

protocolSection.designModule.phases

["PHASE1"]

protocolSection.statusModule.resultsFirstPostDateStruct

null

Study condition terms

• Advanced Solid Tumors (protocolSection.conditionsModule.conditions)
• Non-Small Cell Lung Cancer (protocolSection.conditionsModule.conditions)
• Colorectal Cancer (protocolSection.conditionsModule.conditions)
• Pancreatic Ductal Adenocarcinoma (protocolSection.conditionsModule.conditions)
• Gastric Cancer (protocolSection.conditionsModule.conditions)
• Gastroesophageal Junction Adenocarcinoma (protocolSection.conditionsModule.conditions)
• Biliary Tract Cancer (protocolSection.conditionsModule.conditions)
• Head and Neck Squamous Cell Carcinoma (protocolSection.conditionsModule.conditions)
• Ovarian Cancer (protocolSection.conditionsModule.conditions)

Interventions recorded in this study

• {'armGroupLabels': ['Part 1: ABBV-253 Dose Escalation', 'Part 2: Dose Optimization - ABBV-253 Dose A', 'Part 2: Dose Optimization - ABBV-253 Dose B', 'Part 2: Dose Optimization - ABBV-253 Dose C'], 'description': 'Infusion', 'name': 'ABBV-253', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])

An intervention appearing in a study record does not establish an effect or an approved use.

Drug names recorded in this source

• ABBV-253 (protocolSection.armsInterventionsModule.interventions[].name)

A recorded drug name is not by itself an indication or a condition-specific relationship.

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