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CLINICAL_TRIALS ClinicalTrials.gov record update

Phase I Study of Autologous CD8+ and CD4+ Transgenic T Cells Expressing High Affinity KRASG12V Mutation-Specific T Cell Receptors in Participants With Metastatic Solid Tumors With KRAS G12V Mutations

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Record identity and dates

Source
ClinicalTrials.gov
Source record ID
NCT06043713
Title field or adapter rule
{'original_value': 'Phase I Study of Autologous CD8+ and CD4+ Transgenic T Cells Expressing High Affinity KRASG12V Mutation-Specific T Cell Receptors in Participants With Metastatic Solid Tumors With KRAS G12V Mutations', 'source_field': 'protocolSection.identificationModule.officialTitle'}
Ingested At
2026-10-31T23:27:23.040310+00:00
Published At
2026-10-20T00:00:00+00:00
Record Updated At
2026-10-20
Source Retrieved At
2026-10-31T22:17:52.415050+00:00
Timestamp Basis
ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter
Date limitation
ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Fields recorded by this source

protocolSection.conditionsModule.conditions
["Non-small Cell Lung Cancer", "Pancreas Cancer", "Colon Cancer"]
protocolSection.statusModule.lastUpdatePostDateStruct
{"date": "2026-10-20", "type": "ACTUAL"}
protocolSection.identificationModule.nctId
"NCT06043713"
protocolSection.identificationModule.officialTitle
"Phase I Study of Autologous CD8+ and CD4+ Transgenic T Cells Expressing High Affinity KRASG12V Mutation-Specific T Cell Receptors in Participants With Metastatic Solid Tumors With KRAS G12V Mutations"
protocolSection.statusModule.overallStatus
"RECRUITING"
protocolSection.designModule.phases
["PHASE1"]
protocolSection.statusModule.resultsFirstPostDateStruct
null

Study condition terms

  • Non-small Cell Lung Cancer (protocolSection.conditionsModule.conditions)
  • Pancreas Cancer (protocolSection.conditionsModule.conditions)
  • Colon Cancer (protocolSection.conditionsModule.conditions)

Interventions recorded in this study

  • {'armGroupLabels': ['Treatment (FHA11KRASG12V-TCR)'], 'description': 'Receive IV', 'name': 'Bendamustine', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])
  • {'armGroupLabels': ['Treatment (FHA11KRASG12V-TCR)'], 'description': 'Undergo tissue biopsy', 'name': 'Biopsy', 'type': 'PROCEDURE'} (protocolSection.armsInterventionsModule.interventions[])
  • {'armGroupLabels': ['Treatment (FHA11KRASG12V-TCR)'], 'description': 'Undergo blood sample collection', 'name': 'Biospecimen Collection', 'type': 'PROCEDURE'} (protocolSection.armsInterventionsModule.interventions[])
  • {'armGroupLabels': ['Treatment (FHA11KRASG12V-TCR)'], 'description': 'Undergo CT', 'name': 'Computed Tomography', 'type': 'PROCEDURE'} (protocolSection.armsInterventionsModule.interventions[])
  • {'armGroupLabels': ['Treatment (FHA11KRASG12V-TCR)'], 'description': 'Receive IV', 'name': 'Cyclophosphamide', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])
  • {'armGroupLabels': ['Treatment (FHA11KRASG12V-TCR)'], 'description': 'Undergo ECHO', 'name': 'Echocardiography', 'type': 'PROCEDURE'} (protocolSection.armsInterventionsModule.interventions[])
  • {'armGroupLabels': ['Treatment (FHA11KRASG12V-TCR)'], 'description': 'Receive IV', 'name': 'Fludarabine', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])
  • {'armGroupLabels': ['Treatment (FHA11KRASG12V-TCR)'], 'description': 'Undergo leukapheresis', 'name': 'Leukapheresis', 'type': 'PROCEDURE'} (protocolSection.armsInterventionsModule.interventions[])
  • {'armGroupLabels': ['Treatment (FHA11KRASG12V-TCR)'], 'description': 'Undergo MRI', 'name': 'Magnetic Resonance Imaging', 'type': 'PROCEDURE'} (protocolSection.armsInterventionsModule.interventions[])
  • {'armGroupLabels': ['Treatment (FHA11KRASG12V-TCR)'], 'description': 'Undergo MUGA', 'name': 'Multigated Acquisition Scan', 'type': 'PROCEDURE'} (protocolSection.armsInterventionsModule.interventions[])
  • {'armGroupLabels': ['Treatment (FHA11KRASG12V-TCR)'], 'description': 'Undergo PET', 'name': 'Positron Emission Tomography', 'type': 'PROCEDURE'} (protocolSection.armsInterventionsModule.interventions[])
  • {'armGroupLabels': ['Treatment (FHA11KRASG12V-TCR)'], 'description': 'Receive FHA11KRASG12V-TCR IV', 'name': 'T-cell Receptor-engineered T-cells', 'type': 'BIOLOGICAL'} (protocolSection.armsInterventionsModule.interventions[])

An intervention appearing in a study record does not establish an effect or an approved use.

Drug names recorded in this source

  • Bendamustine (protocolSection.armsInterventionsModule.interventions[].name)
  • Cyclophosphamide (protocolSection.armsInterventionsModule.interventions[].name)
  • Fludarabine (protocolSection.armsInterventionsModule.interventions[].name)

A recorded drug name is not by itself an indication or a condition-specific relationship.

This index keeps the source fields it imported; it may not contain the complete original record. Verify wording and context in the linked source.