CLINICAL_TRIALS ClinicalTrials.gov record update

HERTHENA-PanTumor01 (U31402-277): A Phase 2, Multicenter, Multicohort, Open-Label, Proof of Concept Study of Patritumab Deruxtecan (HER3-DXd; U3-1402) in Subjects With Locally Advanced or Metastatic Solid Tumors

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Record identity and dates

Source: ClinicalTrials.gov
Source record ID: NCT06172478
Title field or adapter rule: {'original_value': 'HERTHENA-PanTumor01 (U31402-277): A Phase 2, Multicenter, Multicohort, Open-Label, Proof of Concept Study of Patritumab Deruxtecan (HER3-DXd; U3-1402) in Subjects With Locally Advanced or Metastatic Solid Tumors', 'source_field': 'protocolSection.identificationModule.officialTitle'}
Ingested At: 2026-10-31T23:27:22.314824+00:00
Published At: 2026-10-26T00:00:00+00:00
Record Updated At: 2026-10-26
Source Retrieved At: 2026-10-31T22:19:02.163121+00:00
Timestamp Basis: ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter
Date limitation: ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

protocolSection.conditionsModule.conditions: ["Advanced Solid Tumor", "Melanoma", "Head and Neck Cancer", "Gastric Cancer", "Ovarian Carcinoma", "Cervical Cancer", "Endometrial Cancer", "Bladder Cancer", "Esophageal Cancer", "Pancreatic Carcinoma", "Prostate Cancer", "Non-small Cell Lung Cancer (NSCLC)", "Lung Cancer", "Breast Cancer"]
protocolSection.statusModule.lastUpdatePostDateStruct: {"date": "2026-10-26", "type": "ACTUAL"}
protocolSection.identificationModule.nctId: "NCT06172478"
protocolSection.identificationModule.officialTitle: "HERTHENA-PanTumor01 (U31402-277): A Phase 2, Multicenter, Multicohort, Open-Label, Proof of Concept Study of Patritumab Deruxtecan (HER3-DXd; U3-1402) in Subjects With Locally Advanced or Metastatic Solid Tumors"
protocolSection.statusModule.overallStatus: "RECRUITING"
protocolSection.designModule.phases: ["PHASE2"]
protocolSection.statusModule.resultsFirstPostDateStruct: null

{'armGroupLabels': ['HER3-DXd Monotherapy'], 'description': 'Intravenous infusion 5.6 mg/kg administered Q3W on Day 1 of each 21-day cycle', 'name': 'HER3-DXd', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])

An intervention appearing in a study record does not establish an effect or an approved use.

A recorded drug name is not by itself an indication or a condition-specific relationship.

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