Phase 2 Single Arm Trial Testing the ZN-c3 WEE1 Inhibitor in Combination With Gemcitabine in Second-Line Advanced Pancreatic Adenocarcinoma

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Record identity and dates

Source

ClinicalTrials.gov

Source record ID

NCT06015659

Title field or adapter rule

{'original_value': 'Phase 2 Single Arm Trial Testing the ZN-c3 WEE1 Inhibitor in Combination With Gemcitabine in Second-Line Advanced Pancreatic Adenocarcinoma', 'source_field': 'protocolSection.identificationModule.officialTitle'}

Ingested At

2026-10-30T23:06:05.665883+00:00

Published At

2026-10-27T00:00:00+00:00

Record Updated At

2026-10-27

Results Posted At

2026-10-27

Source Retrieved At

2026-10-30T22:07:56.375660+00:00

Timestamp Basis

ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Date limitation

ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Fields recorded by this source

protocolSection.conditionsModule.conditions

["Advanced Pancreatic Adenocarcinoma", "Pancreatic Cancer", "Pancreatic Ductal Adenocarcinoma"]

protocolSection.statusModule.lastUpdatePostDateStruct

{"date": "2026-10-27", "type": "ACTUAL"}

protocolSection.identificationModule.nctId

"NCT06015659"

protocolSection.identificationModule.officialTitle

"Phase 2 Single Arm Trial Testing the ZN-c3 WEE1 Inhibitor in Combination With Gemcitabine in Second-Line Advanced Pancreatic Adenocarcinoma"

protocolSection.statusModule.overallStatus

"TERMINATED"

protocolSection.designModule.phases

["PHASE2"]

protocolSection.statusModule.resultsFirstPostDateStruct

{"date": "2026-10-27", "type": "ACTUAL"}

Study condition terms

• Advanced Pancreatic Adenocarcinoma (protocolSection.conditionsModule.conditions)
• Pancreatic Cancer (protocolSection.conditionsModule.conditions)
• Pancreatic Ductal Adenocarcinoma (protocolSection.conditionsModule.conditions)

Interventions recorded in this study

• {'armGroupLabels': ['ZN-c3 + Gemcitabine'], 'description': 'Small molecule inhibitor of the WEE1 tyrosine kinase, tablet taken orally per protocol.', 'name': 'Zentalis', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])
• {'armGroupLabels': ['ZN-c3 + Gemcitabine'], 'description': 'Nucleoside metabolic inhibitor, per standard care via intravenous infusion.', 'name': 'Gemzar', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])

An intervention appearing in a study record does not establish an effect or an approved use.

Drug names recorded in this source

• Zentalis (protocolSection.armsInterventionsModule.interventions[].name)
• Gemzar (protocolSection.armsInterventionsModule.interventions[].name)

A recorded drug name is not by itself an indication or a condition-specific relationship.

This index keeps the source fields it imported; it may not contain the complete original record. Verify wording and context in the linked source.