A Phase IIb Randomised, Double-blind, Placebo-controlled, Multi-centre, Dose-ranging Study of AZD3427 in Participants With Heart Failure and Pulmonary Hypertension Due to Left Heart Disease (WHO Group 2)

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Record identity and dates

Source

ClinicalTrials.gov

Source record ID

NCT05737940

Title field or adapter rule

{'original_value': 'A Phase IIb Randomised, Double-blind, Placebo-controlled, Multi-centre, Dose-ranging Study of AZD3427 in Participants With Heart Failure and Pulmonary Hypertension Due to Left Heart Disease (WHO Group 2)', 'source_field': 'protocolSection.identificationModule.officialTitle'}

Ingested At

2026-10-30T23:06:05.592017+00:00

Published At

2026-10-27T00:00:00+00:00

Record Updated At

2026-10-27

Results Posted At

2026-10-27

Source Retrieved At

2026-10-30T22:07:58.437902+00:00

Timestamp Basis

ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Date limitation

ClinicalTrials.gov API/RSS response retrieval timestamp recorded by Dossier adapter

Fields recorded by this source

protocolSection.conditionsModule.conditions

["Pulmonary Hypertension (World Health Organization Group 2)", "Heart Failure"]

protocolSection.statusModule.lastUpdatePostDateStruct

{"date": "2026-10-27", "type": "ACTUAL"}

protocolSection.identificationModule.nctId

"NCT05737940"

protocolSection.identificationModule.officialTitle

"A Phase IIb Randomised, Double-blind, Placebo-controlled, Multi-centre, Dose-ranging Study of AZD3427 in Participants With Heart Failure and Pulmonary Hypertension Due to Left Heart Disease (WHO Group 2)"

protocolSection.statusModule.overallStatus

"COMPLETED"

protocolSection.designModule.phases

["PHASE2"]

protocolSection.statusModule.resultsFirstPostDateStruct

{"date": "2026-10-27", "type": "ACTUAL"}

Study condition terms

• Pulmonary Hypertension (World Health Organization Group 2) (protocolSection.conditionsModule.conditions)
• Heart Failure (protocolSection.conditionsModule.conditions)

Interventions recorded in this study

• {'armGroupLabels': ['AZD3427 Dose A', 'AZD3427 Dose B', 'AZD3427 Dose C'], 'description': 'The participants will receive AZD3427 SC injection single dose of either Dose A or Dose B or Dose C every 2 weeks for 24 weeks.', 'name': 'AZD3427', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])
• {'armGroupLabels': ['Placebo'], 'description': 'The participants will receive SC injection of placebo single dose every 2 weeks for 24 weeks.', 'name': 'Placebo', 'type': 'DRUG'} (protocolSection.armsInterventionsModule.interventions[])

An intervention appearing in a study record does not establish an effect or an approved use.

Drug names recorded in this source

• AZD3427 (protocolSection.armsInterventionsModule.interventions[].name)
• Placebo (protocolSection.armsInterventionsModule.interventions[].name)

A recorded drug name is not by itself an indication or a condition-specific relationship.

This index keeps the source fields it imported; it may not contain the complete original record. Verify wording and context in the linked source.