Clinical Trial Results: Phase Ib/2a Drug-drug Interaction Study of a Combination of 45mg Dextromethorphan With 105 mg Bupropion [Phase 1, Phase 2]

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Summary

Phase Ib/2a study evaluating a combination of dextromethorphan with bupropion for addiction/opioid use disorders; results completed with results posted.

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Diseases / indications

• Addiction
• Opioid Use Disorder
• Substance Use Disorder

Drugs mentioned

• Dextromethorphan (dextromethorphan)
• bupropion (bupropion)

Snippet

Sponsor: Virginia Commonwealth University | Conditions: Addiction, Opioid Use | Phase 1, Phase 2 | Status: COMPLETED | Results posted: 2026-08-19