Clinical Trial Results: Effect of Guanfacine on Opioid-induced Hyperalgesia (OIH) and Tolerance [Phase 4]

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Summary

Phase 4 trial investigating guanfacine for opioid-induced hyperalgesia and tolerance in chronic pain; study terminated with posted results.

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Diseases / indications

• Pain

Drugs mentioned

• Guanfacine (guanfacine)

Snippet

Sponsor: Massachusetts General Hospital | Conditions: Chronic Pain | Phase 4 | Status: TERMINATED | Results posted: 2026-07-31