Clinical Trial Update: A Study Evaluating the Efficacy and Safety of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibitors [Phase 3]

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Summary

Phase 3 trial comparing crovalimab to eculizumab in treatment-naïve PNH patients; study status active/not recruiting with results posted in 2025.

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Diseases / indications

• Paroxysmal Nocturnal Hemoglobinuria

Drugs mentioned

• Crovalimab (crovalimab)
• Eculizumab (eculizumab)

Snippet

Sponsor: Hoffmann-La Roche | Conditions: Paroxysmal Nocturnal Hemoglobinuria | Phase 3 | Status: ACTIVE_NOT_RECRUITING | Results posted: 2025-11-10