Clinical Trial Update: Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors [Phase 1]

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Summary

Phase 1 trial investigating palbociclib isethionate in pediatric CNS tumors; status terminated with posted results in 2020.

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Diseases / indications

• Childhood Anaplastic Astrocytoma
• Childhood Anaplastic Oligoastrocytoma
• Childhood Anaplastic Oligodendroglioma
• Childhood Brain Stem Glioma
• Childhood Cerebellar Astrocytoma
• Childhood Cerebral Astrocytoma
• Childhood Choroid Plexus Tumor
• Childhood Ependymoblastoma
• Childhood Giant Cell Glioblastoma
• Childhood Glioblastoma
• Childhood Gliomatosis Cerebri
• Childhood Gliosarcoma
• Childhood Grade Iii Meningioma
• Childhood High-grade Cerebellar Astrocytoma
• Childhood High-grade Cerebral Astrocytoma
• Childhood Medulloblastoma
• Childhood Pineoblastoma
• Childhood Supratentorial Primitive Neuroectodermal Tumor

Drugs mentioned

• Palbociclib isethionate (palbociclib isethionate)

Snippet

Sponsor: Pediatric Brain Tumor Consortium | Conditions: Childhood Choroid Plexus Tumor, Childhood Ependymoblastoma | Phase 1 | Status: TERMINATED | Results posted: 2020-04-08