Enhancement of Cetuximab-Induced Antibody-Dependent Cellular Cytotoxicity (ADCC) With Lenalidomide in Advanced Solid Tumors: A Phase I/IB Study

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Record identity and dates

Source

ClinicalTrials.gov

Source record ID

NCT01254617

Title field or adapter rule

protocolSection.identificationModule.officialTitle

Ingested At

2026-04-28T10:37:47.495459+00:00

Published At

2020-03-13T00:00:00+00:00

Record Updated At

2020-03-13

Timestamp Basis

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Date limitation

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Fields recorded by this source

protocolSection.conditionsModule.conditions

["Recurrent Colon Carcinoma", "Recurrent Hypopharyngeal Squamous Cell Carcinoma", "Recurrent Laryngeal Squamous Cell Carcinoma", "Recurrent Laryngeal Verrucous Carcinoma", "Recurrent Lip and Oral Cavity Squamous Cell Carcinoma", "Recurrent Metastatic Squamous Cell Carcinoma in the Neck With Occult Primary", "Recurrent Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma", "Recurrent Nasopharyngeal Keratinizing Squamous Cell Carcinoma", "Recurrent Oral Cavity Verrucous Carcinoma", "Recurrent Oropharyngeal Squamous Cell Carcinoma", "Recurrent Rectal Carcinoma", "Recurrent Salivary Gland Carcinoma", "Salivary Gland Squamous Cell Carcinoma", "Squamous Cell Carcinoma Metastatic in the Neck With Occult Primary", "Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7", "Stage IV Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7", "Stage IVA Colon Cancer AJCC v7", "Stage IVA Laryngeal Squamous Cell Carcinoma AJCC v7", "Stage IVA Laryngeal Verrucous Carcinoma AJCC v7", "Stage IVA Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7", "Stage IVA Major Salivary Gland Cancer AJCC v7", "Stage IVA Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v7", "Stage IVA Oral Cavity Cancer AJCC v6 and v7", "Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7", "Stage IVA Rectal Cancer AJCC v7", "Stage IVB Colon Cancer AJCC v7", "Stage IVB Laryngeal Squamous Cell Carcinoma AJCC v7", "Stage IVB Laryngeal Verrucous Carcinoma AJCC v7", "Stage IVB Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7", "Stage IVB Major Salivary Gland Cancer AJCC v7", "Stage IVB Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v7", "Stage IVB Oral Cavity Cancer AJCC v6 and v7", "Stage IVB Oropharyngeal Squamous Cell Carcinoma AJCC v7", "Stage IVB Rectal Cancer AJCC v7", "Stage IVC Laryngeal Squamous Cell Carcinoma AJCC v7", "Stage IVC Laryngeal Verrucous Carcinoma AJCC v7", "Stage IVC Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7", "Stage IVC Major Salivary Gland Cancer AJCC v7", "Stage IVC Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v7", "Stage IVC Oral Cavity Cancer AJCC v6 and v7", "Stage IVC Oropharyngeal Squamous Cell Carcinoma AJCC v7", "Tongue Carcinoma"]

protocolSection.statusModule.lastUpdatePostDateStruct.date

"2020-03-13"

protocolSection.identificationModule.nctId

"NCT01254617"

protocolSection.identificationModule.officialTitle

"Enhancement of Cetuximab-Induced Antibody-Dependent Cellular Cytotoxicity (ADCC) With Lenalidomide in Advanced Solid Tumors: A Phase I/IB Study"

protocolSection.statusModule.overallStatus

"COMPLETED"

protocolSection.designModule.phases

["PHASE1"]

protocolSection.statusModule.resultsFirstPostDateStruct.date

""

Study condition terms

• Recurrent Colon Carcinoma (protocolSection.conditionsModule.conditions)
• Recurrent Hypopharyngeal Squamous Cell Carcinoma (protocolSection.conditionsModule.conditions)
• Recurrent Laryngeal Squamous Cell Carcinoma (protocolSection.conditionsModule.conditions)
• Recurrent Laryngeal Verrucous Carcinoma (protocolSection.conditionsModule.conditions)
• Recurrent Lip and Oral Cavity Squamous Cell Carcinoma (protocolSection.conditionsModule.conditions)
• Recurrent Metastatic Squamous Cell Carcinoma in the Neck With Occult Primary (protocolSection.conditionsModule.conditions)
• Recurrent Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma (protocolSection.conditionsModule.conditions)
• Recurrent Nasopharyngeal Keratinizing Squamous Cell Carcinoma (protocolSection.conditionsModule.conditions)
• Recurrent Oral Cavity Verrucous Carcinoma (protocolSection.conditionsModule.conditions)
• Recurrent Oropharyngeal Squamous Cell Carcinoma (protocolSection.conditionsModule.conditions)
• Recurrent Rectal Carcinoma (protocolSection.conditionsModule.conditions)
• Recurrent Salivary Gland Carcinoma (protocolSection.conditionsModule.conditions)
• Salivary Gland Squamous Cell Carcinoma (protocolSection.conditionsModule.conditions)
• Squamous Cell Carcinoma Metastatic in the Neck With Occult Primary (protocolSection.conditionsModule.conditions)
• Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7 (protocolSection.conditionsModule.conditions)
• Stage IV Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7 (protocolSection.conditionsModule.conditions)
• Stage IVA Colon Cancer AJCC v7 (protocolSection.conditionsModule.conditions)
• Stage IVA Laryngeal Squamous Cell Carcinoma AJCC v7 (protocolSection.conditionsModule.conditions)
• Stage IVA Laryngeal Verrucous Carcinoma AJCC v7 (protocolSection.conditionsModule.conditions)
• Stage IVA Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7 (protocolSection.conditionsModule.conditions)
• Stage IVA Major Salivary Gland Cancer AJCC v7 (protocolSection.conditionsModule.conditions)
• Stage IVA Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v7 (protocolSection.conditionsModule.conditions)
• Stage IVA Oral Cavity Cancer AJCC v6 and v7 (protocolSection.conditionsModule.conditions)
• Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7 (protocolSection.conditionsModule.conditions)
• Stage IVA Rectal Cancer AJCC v7 (protocolSection.conditionsModule.conditions)
• Stage IVB Colon Cancer AJCC v7 (protocolSection.conditionsModule.conditions)
• Stage IVB Laryngeal Squamous Cell Carcinoma AJCC v7 (protocolSection.conditionsModule.conditions)
• Stage IVB Laryngeal Verrucous Carcinoma AJCC v7 (protocolSection.conditionsModule.conditions)
• Stage IVB Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7 (protocolSection.conditionsModule.conditions)
• Stage IVB Major Salivary Gland Cancer AJCC v7 (protocolSection.conditionsModule.conditions)
• Stage IVB Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v7 (protocolSection.conditionsModule.conditions)
• Stage IVB Oral Cavity Cancer AJCC v6 and v7 (protocolSection.conditionsModule.conditions)
• Stage IVB Oropharyngeal Squamous Cell Carcinoma AJCC v7 (protocolSection.conditionsModule.conditions)
• Stage IVB Rectal Cancer AJCC v7 (protocolSection.conditionsModule.conditions)
• Stage IVC Laryngeal Squamous Cell Carcinoma AJCC v7 (protocolSection.conditionsModule.conditions)
• Stage IVC Laryngeal Verrucous Carcinoma AJCC v7 (protocolSection.conditionsModule.conditions)
• Stage IVC Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7 (protocolSection.conditionsModule.conditions)
• Stage IVC Major Salivary Gland Cancer AJCC v7 (protocolSection.conditionsModule.conditions)
• Stage IVC Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v7 (protocolSection.conditionsModule.conditions)
• Stage IVC Oral Cavity Cancer AJCC v6 and v7 (protocolSection.conditionsModule.conditions)
• Stage IVC Oropharyngeal Squamous Cell Carcinoma AJCC v7 (protocolSection.conditionsModule.conditions)
• Tongue Carcinoma (protocolSection.conditionsModule.conditions)

Intervention details are not present in the imported fields for this record. No drug-condition relationship is inferred from co-listing.

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